A total of 23 samples tested Ab reactive by both the Determine HIV Early Detect test and the reference LIAISON XL HIV assay. Then it gave a sensitivity of 100% (95% CI 85.2, 100.0), a specificity of 100% (95% CI 98.7, 100) and an accuracy of 100% (95% CI 98.8, 100) for the...
Methods A total of 416 anti HCV screening test reactive donor samples collected from 13 blood centers from three cities in Turkey were tested in duplicate by Ortho HCV Ab Version 3.0 and Radim HCV Ab. All the repeat reactive samples were tested by INNO-LIA HCV Ab 3.0 or Chiron RIBA HCV ...
Ottiger C, Gygli N, Huber AR: Detection limit of architect hepatitis C core antigen assay in correlation with HCV RNA, and renewed confirmation algorithm for reactive anti-HCV samples. J Clin Virol. 2013, 58: 535-540. 10.1016/j.jcv.2013.08.028. Article CAS PubMed Google Scholar Shen T...
Non-reactive antibodies are removed with the wash buffer. Human IgGs bound to the antigen are reacted with anti-human IgG peroxidase conjugate and visualized by subsequent reactions with a chromogenic substrate. Positive sample generates a medium to dark blue color. No color or very pale blue ...
A combined hepatitis C virus (HCV) antigen-antibody assay was evaluated for 115 seronegative individuals with occult HCV infection. The assay was reactive ... JA Quiroga,I Castillo,M Pardo,... - 《Journal of Clinical Microbiology》 被引量: 22发表: 2006年 ...
These data demonstrate that entry inhibition may also serve as a novel salvage antiviral mechanism in patients who do not respond well to other HCV DAAs and inform the development of novel HCV vaccine antigens that would allow for the development of a broadly reactive neutralizing antibody response...
Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway in monocytes and hepatocytes. J Immunol 2010; 185: 6985–6998. 32 Mazan-Mamczarz K, Hagner PR, Zhang Y, Dai B, Lehrmann E, ...
All specimens that were reactive or borderline reactive for either antigen or antibody were confirmed by quantitative HCV PCR (COBAS® AmpliPrep/ COBAS® TaqMan® HCV, v2.0, Roche Basel, Switzerland). HIV and Syphilis rapid test results were not entered into the...
Additionally, these compounds’ structural alert or toxicity prediction is higher than the remaining representatives due to their possession of known toxic and reactive substructures, including diazo, imine, quaternary nitrogen, sulfonic acid, phthalimide, and Michael acceptor. The predicted overall ...
(insulin receptor substrate 1,IRS-1) 丝氨酸磷酸化、IRS-2 去磷酸化、下调葡萄糖转运蛋白4(glucose transporter 4, GLUT4) 水平, 从而诱导胰岛素抵抗, 最终使肝细胞内游离脂肪酸水平升高, 促进脂肪肝的发生(路径c) ; HCV 通过诱导活性氧簇...