In hemodynamic studies, amlodipine has not been associated with a negative inotropic effect when administered in the therapeutic dose range to intact animals and man, even when coadministered with beta-blockers to man. Similar findings, however, have been observed in normal or well-compensated ...
Valsartan peak plasma concentration is reached 2 to 4 hours after dosing. Valsartan showsbi-exponential decaykineticsfollowing intravenous administration, with an average elimination half-life of about 6 hours. Absolute bioavailability for the capsule formulation is about 25% (range 10% to 35%). Food...
symptoms of a highpotassiumblood level (such as muscle weakness, slow or irregular heartbeat), unusual change in the amount of urine (not including the normal increase in urine when you first start this drug), or severe or persistent diarrhea. ...
NK cells are one of the first lymphocyte populations to recover after HCT, reaching normal population numbers months before recovery of memory and effector CD8+ lymphocytes, which would agree with the timing of relapse protection observed in our cohort.23 Moreover, graft-versus-leukemia effects of...
Albendazole (ABZ) is a microtubule-targeting anthelmintic with a remarkable activity against a variety of human cancer cells. In this study, we examined if the antitumor activity of ABZ could be enhanced by its combination with other microtubule-binding
Amellem O, Stokke T, Sandvik JA, Smedshammer L, Pettersen EO (1997) Hypoxia-induced apoptosis in human cells with normal p53 status and function, without any alteration in the nuclear protein level. Exp Cell Res 232: 361–370 Article CAS PubMed Google Scholar Bhattacharyya NP, Skandalis ...
0=normal; 0.5=focal and rare; 1=focal and mild; 2=diffuse and mild; 3=diffuse and moderate; 4=diffuse and severe, adapted from (Hill, G. R. et al. Total body irradiation and acute graft-versus-host disease: the role of gastrointestinal damage and inflammatory cytokines. Blood 90, 3204...
amlodipine has not been associated with a negative inotropic effect when administered in the therapeutic dose range to intact animals and man, even when coadministered with beta-blockers to man. Similar findings, however, have been observed in normals or well-compensated patients with heart failure...
Blood pressure is given as a reading of two numbers, such as 110/70. The higher number (systolic) is the pressure when the heart beats. The diastolic, or lower number shows the pressure between the heartbeats, while the relaxed heart is refilling with blood. Normal blood pressure readings ...