参考信息 HCMV Infection Reduces Nidogen-1 Expression, Contributing to Impaired Neural Rosette Development in Brain Organoids.J Virol. 2023 May 31;97(5):e0171822. doi: 10.1128/jvi.01718-22.PMID: 37125912 PMCID: PMC10231252. 往期推荐 胃癌类器官培养图鉴 【Nature Protocols】系列:如何培养血管类器...
参考文献 Han Dong-mei, Yin Wen, Chen Xie-qun. The evolution about the treatment of HCMV-infection by McAb [J]. Foreign Med Sci: Epidemiol Loimol,2004,31(03): 158-160.
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but the mechanisms underlying these disorders are far from well-defined. HCMV infection has been shown to dysregulate the Notch signaling pathway in human neural progenitor cells (NPCs). As an important downstream effector...
The present invention provides reagents for diagnosis of human cytomegalovirus infection include: human cytomegalovirus DNA PCR primers, miRNA-UL112-3p forward PCR primers and PCR miRNA-UL112-5p Forward amplification primers. 本发明所述试剂,采用PCR方法,分别对非肿瘤患者(其中HCMV特异性CD8+T淋巴细胞...
生成的OE和KO胶质瘤细胞以5的感染倍数(multiplicity of infection, MOI)感染。HCMV基因以时间级联方式表达,通过RT-qPCR检测了三个时间类别的代表性基因——即早期(UL123和UL122编码IE1和IE2)、早期(UL44编码UL44)和晚期(UL99编码pp28)...
To determine the impact of HCMV infection on astrocytes, we generated low﹑assage clinical HCMV isolates for infection of human fetal astrocytes (HFA) and astroglioma (U251) cells. To assess the ability of HCMV to produce Aβ, we infected HFAs and U251s with HCMV for 3days then ...
2019版）. 器官移植 2019, 10(2):7.[9] 中华医学会器官移植学分会 中: 中国实体器官移植受者巨细胞病毒感染诊疗指南(2016版). 中华器官移植杂志 2016, 37(9):5.[10]张路坤, 王辉, 孙丽琴, et al. Analysis on 431 HIV/AIDS patients with cytomegalovirus infection%431例HIV/AIDS患者巨细胞病毒感染情况...
⑵无症状性感染（asymptomaticinfection）：指体内病毒复制状态有二种情况：一是有病毒复制，若足以引起靶器官或组织损害，临床表现有体征和器官功能改变，称之为亚临床型感染（subclinicalinfection）；若未引起靶器官损害，则无相应体征和功能变化，为真正的无症状性感染。后者是病毒处于潜伏状态或呈不全感染。性状 巨...