Isolated hCG subunits have occasionally been reported to bind, but this binding can usually be attributed either to contaminating dimer hCG or to homodimerization of 尾-subunits, which mimics the conformation of the native hormone. There is no convincing evidence to support hCG binding to any other...
Gonadotropin Releasing Hormone (GnRH) exhibits some attractive features, including its presence in both sexes, which suggests the possibility of a con- traceptive vaccine active in males and females. Unfortunately, because of GnRH's role in sex steroid production, fertility, ...
consisting of a protein hormone, a non-hormonal protein, or a fragment of either which has been chemically modified outside the body of the animal, the protein hormone, non-hormonal protein or fragment having the properties of (a) in unmodified form, being non-immunogenic to the mammal and ...
the target gene of miR-125b, the expression of MMP26 mRNA and protein was examined in human EECs after transfection with miR-125b mimics, which could up-regulate miR- 125b about 500-fold (Fig. 4A). Although MMP26 mRNA showed no change (Fig. 4B), the expression of MMP26 protein...
mimics with the subunit proteins of the luteinizing hormone and the follicle-stimulating hormone. In comparison, the beta subunit is larger than the alpha subunit. Overall, the hCG hormone has a hydrophobic core and a hydrophilic outer region. This enables the easy dissolution of the hormone. ...