sensitivity of NC-AMRI compared to US screening, but a significantly higher diagnostic yield while maintaining a comparable false referral rate [25]. In another prospective study evaluating DWI alone, sensitivity was 83% and specificity 98% for detection of HCC [26]. While this study was relative...
There is a growing evidence that MAFLD-related HCC seems to be different from HCCs of other causes pathologically, so the purpose of our study was to assess the effect of MAFLD on the prognosis of HCC regarding outcome after management of HCC and survival rate in comparison to a group of ...
(including transplant)**1122200Systemic2654631Overall Survival (months)29.526.834.717.524.117.314.925.3*Several patients received one or more types of therapy.**All transplant patients received ablation therapy.#Sociodemographic data.#*Several patients received one or more types of therapy.#**All ...
Increased expression of TH was found facilitates the survival of HCC patients. In addition, decreased TH indicated larger tumor size, much more numbers of tumor, higher level of AFP, and the presence of cirrhosis. TH effectively impairs the growth and metastasis of HCC cells, a process ...
Secondary endpoints were symptom response duration, toxicities, overall survival (OS), AFP response, and radiological response. Symptom response duration was defined as the period from date of RT to the date of index symptom deterioration. OS was calculated from the date of RT to the date of ...
10]. The metabolic intermediates generated during aerobic glycolysis can be used for biosynthesis of tumor biological macromolecules to meet the needs of rapid growth. Moreover, lactate production also provides an acidic environment, suppresses immune cell function, and further promotes the survival of ...
Among the family members, ACSL4 is the most up-regulated enzyme, associated with poor survival in HCC patients, particularly in post-recurrent TACE-treated patients in a Singapore cohort. ACSL4 is essential for HCC cell survival in response to glucose starvation, rather than to hypoxia or to ...
Statistical analysis was performed in October 2012. Differences between groups were examined for statistical significance using the Mann–WhitneyU-test, logistic regression test, or squared test, as appropriate. The cumulative survival rate was calculated from the date of initiation of the HAIC and so...
To the miR-378 family belong miR-378a,b,c,d,e,f,h,I and miR-422 all expressed in blood, while in serum only miR-378a,c,h,I are detectable (TableS3). MiR-378a has been reported to be involved in cell survival, tumor growth and angiogenesis45. In liver it inhibits the hepatic...
To investigate the expression pattern of SIRT7 and USP39 in HCC cells, we used the web tool Kaplan-Meier database and found that the aberrant expression of SIRT7 and USP39 transcripts were reversely correlated with overall survival (OS) of patients, whereas MYST1 showed a positive correlation...