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Statistical analysis were performed by two-tailed Student’s t-test. Full size image We subsequently investigated the regulatory role of DUSP22 on the pathological progression of NASH to HCC in DUSP22HepKO and DUSP22HepOE mice treated with DEN (25 mg/kg; at 2 weeks old) and a 24-...
2A). Transwell invasion assays demonstrated that the number of invasion cells were reduced in HCC cells overexpressing Flag-TH (Fig. 2B, C). In addition, the wound-healing assay demonstrated that the overexpression of TH suppressed the migration of HCC cells (Fig. 2D, E). To further confirm...
Statistical analysis of the differences between two groups was performed using a two-tailed Student’s t test, and multiple group comparisons were performed using one-way or two-way ANOVA followed by Tukey’s post hoc test. The significance thresholds were defined as statistically significant (∗...
The data were presented as mean ± SD, *P < 0.05, **P < 0.01, by Student's t-test proliferation decreasing in the CDK6 shRNA cells com- pared to the circ-ZEB1.33 shRNA cells, this result might indicate that there might be other mechanism besides the circ-ZEB1.33/miR-...
The data were presented as mean ± SD, *P < 0.05, **P < 0.01, by Student's t-test proliferation decreasing in the CDK6 shRNA cells com- pared to the circ-ZEB1.33 shRNA cells, this result might indicate that there might be other mechanism besides the circ-ZEB1.33/miR-...
Student's t-test was used to compare the means. For both tests, a value of P,0.05 was considered statistically significant. The Kaplan–Meier product limit estimator was used to graph overall survival. Univariate analysis was performed with the log-rank test. Cox proportional hazards regression ...
Student's t-test was used to compare the means. For both tests, a value of P<0.05 was considered statistically significant. The Kaplan–Meier product limit estimator was used to graph overall survival. Univariate analysis was performed with the log-rank test. Cox proportional hazards regression ...
Student's t test was applied to compares the differ- ence between the two groups. If the absolute value of the β difference level of a differential methylation point (DMP)'s (|βtumor − βnormal|) > 0.4 and the p value < 0.001, it was considered meaningful. As a ...
Statistical analysis was conducted using the GraphPad Prism Software (Version 7). The differences between two groups were estimated by a two-tailed Student’s t-test. Spearman correlation coefficients were calculated to evaluate the correlations....