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The importance of HCC codingLori Zimmerman
The Cas9 stable-expressing MHCC97L cells (MHCC97L-Cas9) were established by lentiviral transduction of Cas9 coding sequence into the genome of cells. MHCC97L was a gift from Fudan University (Professor Z.Y. Tang, Shanghai, China). The expression of Cas9 protein was confirmed by a Cas9-spe...
Inflamed and non-inflamed classes of HCC: a revised immunogenomic classification. Gut. 2023; 72:129–40. https://doi.org/10.1136/gutjnl-2021-325918 PMID:35197323 16. Li B, Cao Y, Li Y, Cheng C, Yu D. Letter to the editor: the inflamed subclass predicts immunotherapy response - ...
comprising of a family of PN classes is employed. In the designed HPN model, places signifies gene, mRNA, miRNA, protein and compounds etc involved in sorafenib resistance and transitions depict the interactions, processes or reactions (e.g., de-/activation, de-/phosphorylation, transcription, ge...
Regarding the efficacy of drugs, it must be considered that the two main classes act as inhibitors of enzymatic cascades or receptors involved in carcinogenesis. However, these mechanisms, although important from a molecular point of view, are not the only ones responsible. This involves an ...