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and provides advanced capabilities for professional webmasters. Lion Server makes it easy for groups to collaborate by enabling Wiki in the Server application. To use your own custom web content, you can also replace this placeholder page by adding your own index file to the folder at /Library...
Thus far, the clinical application of conventional targeted therapeutics has been constrained by the reactivation of the targeted signaling pathway or the adoption of alternative signaling pathways [27]. A growing body of evidence suggests that the targeting of transcription factors holds promise as a ...
Tumor recurrence after radiofrequency ablation (RFA) affects the survival rate of patients and limits its clinical application. Tumor recurrence around the
Targeting MELK in tumor cells and tumor microenvironment: from function and mechanism to therapeutic application Pengfei Su Qiliang Lu Weiwei Jin Clinical and Translational Oncology (2024)Download PDF Sections Figures References Abstract Introduction Materials and methods Results Discussion Conclusions Data...
Currently, 5-aza-CdR is the most widely used meth- ylation inhibitor, which has good prospects for clini- cal application since it causes demethylation of most highly-methylated tumor-suppressor genes, inhibit- ing tumor progression in vitro and in vivo [9]. In recent decades, molecular ...
Crosstalk among m(6)A RNA methylation, hypoxia and metabolic reprogramming in TME: from immu- nosuppressive microenvironment to clinical application. J Hematol Oncol. 2022;15:84. 36. Xue C, Chu Q, Zheng Q, Jiang S, Bao Z, Su Y, et al. Role of main RNA modifications in cancer: N(6...
Following being sharply frozen with liquid nitrogen, all the tissues were then preserved at −80°C until application. Each patient involved in this study was treated with no other therapies and signed the written informed consent before operation. Cell culture Human HCC cell lines (Hep 3B and...
The role of cell adhesion molecule in cancer progression and its application in cancer therapy. Acta Biochim Pol 2004; 51: 445–457. 2. Kawauchi T. Cell adhesion and its endocytic regulation in cell migration during neural development and cancer metastasis. Int J Mol Sci 2012; 13: 4564–...
et al. Design and application of a cytokine-receptor-based interaction trap. Nat. Cell Biol. 3, 1114–1119 (2001). Article CAS Google Scholar Shakoori, A. et al. Identification of a five-pass transmembrane protein family localizing in the Golgi apparatus and the ER. Biochem. Biophys. Res...