Well, getting the right letters together still matters, and in the healthcare world, three letters to pay close attention to are HCC. Those letters stand forHierarchical Condition Category (HCC)coding. They are at the heart of calculating patients’ risk scores, predicting healthcare expenditures,...
DNA and proteins (1). These small particles of 40 to 5,000 nm in diameter are released by several cells into the extracellular matrix. While they were previously considered as a means to discard cellular metabolic
MicroRNAs are small noncoding RNAs that regulate gene expression by targeting messenger RNAs (mRNAs) through translational repression or RNA degradation. Many fundamental biological processes are...
In the current study, we have demonstrated for the first time that cell competition promotes drug resistance development in HCC by facilitating the dominant growth of lenvatinib-resistant HCC cells. Mechanistically, the hyperactivation of BNIP3-mediated mitophagy in lenvatinib-resistant HCC cells promotes...
The role of long noncoding RNA (lncRNAs) had been demonstrated in different types of cancer, including hepatocellular carcinoma. This study was intended to investigate the role of lncRNA small nucleolar RNA host gene 5 (SNHG5) in HCC proliferation and th
meaning their actual plan liability was 2 times higher than what was predicted. Risk scores for beneficiaries taking antidiabetics was higher than 1; however the RxHCC model prediction was close to 1 (0.843). This means the predictive plan liability for these beneficiaries was close to their ac...
refractory to the treatment, provide additional rational for the neoadjuvant use of immunotherapy. This study aimed to explore the “neoadjuvant” therapy of HCC, which means the tumors must be clearly and definitely “resectable”; in BCLC staging system, resection/(ablation/transplantation) is only...
Values are means+SEM, *p < 0.05 and ***p < 0.001, compared to control group. Two-tailed unpaired T-Test was used for statistical analysis by SPSS 19.0 software Full size image Discussion Despite the progress in understanding carcinogenesis and therapeutic approaches, the prognosis of ...
. Western blotting was performed to determine the distribution of β-catenin proteins in the nucleus and cytoplasm in SK-hep-1 after cells were knockdown (F) and overexpression (G) of USP39. All the data are representative of at least three independent experiments and presented as the means...
tumor ablation, a probe is injected into the liver and the tumor is destroyed by radio or microwaves or cryotherapy. In embolization procedures, the blood supply of the tumor is blocked by mechanical or chemical means. High energy radio waves can be used to destroy the tumor in radiation ...