1 DAA药物显著改善丙肝患者预后 经治疗的慢性丙型肝炎（CHC）通常变为进行性肝纤维化、肝硬化和肝细胞癌（HCC）。在病毒学治愈的CHC患者中，基于干扰素的治疗已被证明与降低总体死亡率和肝脏相关并发症(如HCC和失代偿性肝病)以及非肝脏相关并发症(如非肝癌、糖尿病以及慢性肾病)有关。然而，基于干扰素的治疗缺乏疗效...
They also stated that no significant difference between the two groups regarding portal vein invasion or extrahepatic spread (p = 0.83and 0.06). Finally, they concluded that CHC patients treated with DAAs had larger de novo HCC lesions than untreated patients, however, there was no difference in...
1、DAA药物显著改善丙肝患者预后 经治疗的慢性丙型肝炎(CHC)通常变为进行性肝纤维化、肝硬化和肝细胞癌(HCC)。在病毒学治愈的CHC患者中,基于干扰素的治疗已被证明与降低总体死亡率和肝脏相关并发症(如HCC和失代偿性肝病)以及非肝脏相关并发症(如非肝癌、糖尿病以及慢性肾病)有关。然而,基于干扰素的治疗缺乏疗效,耐...
但已经证明,肝纤维化分期F3的慢性丙型肝炎(CHC)患者在实现SVR后仍有发展为HCC的风险。 本届AASLD年会上发表一项大型队列研究最新结果,该研究旨在探究明确F3期CHC患者接受DAA治疗并确定SVR后HCC的发生风险。研究结果显示,HCC的发病率低于成...
Objective:To determine the prognostic factors of ruptured hepatocellular carcinoma (HCC) and report the management of patients with spontaneous rupture of ... RF Keate,R Shaffer - 《Gastrointestinal Endoscopy》 被引量: 37发表: 1992年 Effects of interactions between environmental factors and KIF1B gen...
[7] Rinaldi L, Perrella A, Guarino M, et al. Incidence and risk factors of early HCC occurrence in HCV patients treated with direct acting antivirals: a prospective multicentre study. J Transl Med,2019,17:292. [...
Although diabetes mellitus (DM) is known to increase the risk of hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), the impact of dynamic glucose status on HCC occurrence in chronic hepatitis C (CHC) patients receiving antiviral therapy is unclear. In total, 1112 biopsy-proven patie...
Patients were also stratified for HCC risk based on genomic and imaging data with inclusion of screening for circulating tumor cells. Methods: Our cohort included 1,400 patients and approximately 500 had liver biopsies. Our retrospective prospective study included 60 patients with CHC and a baseline...
[17] Innes H, Jepsen P, McDonald S, et al. Performance of models to predict hepatocellular carcinoma risk among UK patients with cirrhosis and cured HCV infection. JHEP Rep, 2021,3:100384. [18] Ooka Y, Miho K...
OBJECTIVES: To examine the efficacy and prognostic benefits of radiotherapy (RT) in patients who have unresectable advanced hepatocellular carcinoma (HCC) ... T Nakazawa,S Adachi,M Kitano,... - 《Oncology》 被引量: 140发表: 2008年 Assessing the health of coastal marine ecosystems: A holistic ...