High HbA1c levels indicate poorer control of diabetes than levels in the normal range. HbA1c is typically measured to determine how well a type 1 or type 2 diabetes treatment plan (including medications, exercise, or dietary changes) is working. What Is Hemoglobin A1c? Hemoglobin is the oxygen...
The Diabetes Control and Complications Trial (DCCT) demonstrated that a regimen of intensive therapy aimed at maintaining near-normal blood glucose values ... None - 《Diabetes》 被引量: 3808发表: 1995年 Therapy focused on lowering postprandial glucose, not fasting glucose, may be superior for lo...
However, we experienced two cases of high HbA1c levels with normal glucose tolerance confirmed by 75 g oral glucose tolerance test (75 g OGTT); thus, these cases might have been misdiagnosed as diabetes if we had not measured plasma glucose levels. If HbA1c is used as the sole means of...
HbA Patients with diabetes, determined by higher than normal hemoglobin A1c(HbA1c) levels, show greater increases in cognitive decline over 10 years compared to those with normal blood sugar, suggesting that good blood glucose control could help slow possible progression to dementia. "To the best ...
As we described above, in the ACCORD trial, the use of aggressive glycemic treatment to target normal HbA1c levels elevated the risk of mortality, and did not significantly reduce major CVD events in participants with T2D [9]. Similarly, the Degludec vs. Insulin Glargine in Participants with ...
Postprandial plasma glucose: a good index of glycemic control in type 2 diabetic patients having near-normal fasting glucose levels Diabetes Res. Clin. Pract. (1999) The Diabetes Control and Complications Trial Research Group, The effect of intensive treatment of diabetes on the... UK Prospective...
The Kolmogorov-Smirnov test was applied to examine normal distribution. Continuous variables are expressed as mean ± SD and were compared among non-diabetic, diabetic controlled, and diabetic uncontrolled groups by analysis of variance (ANOVA) followed by Scheffe’s post-hoc test for pairwise compar...
Under normal circumstances, approximately 97% of adult haemoglobin is haemoglobin A (HbA), which itself is composed of four globin chains: two alpha and two beta chains (Wang and Hng, 2021). When glucose binds covalently to the beta chain of HbA, the resulting form of the molecule then per...
We acknowledge that missing data may have occurred preferentially in people with normal or close to normal risk factors (i.e. missing not at random), possibly leading to bias in the magnitude of the association and an underestimation of the differentials in risk factor levels. Fifth, people ...
R. Near normal HbA1c with stable homeostasis: the ultimate targets/aim of diabetes therapy. Rev. Endocr. Metab. Disord. 17, 91–101 (2016). This paper provides contemporary in-depth discussion of the importance of postprandial hyperglycaemia and glucose variability in assessing the treatment of ...