根据检测技术的发展和市场要求,NGSP不断的收紧评判标准,比如2019年的评判标准就从2018年的6%提高到了5%,这对产品的准确度是一个严苛的考验。 从一定意义上来说,通过NGSP认证,就等于糖化血红蛋白的检测已符合国际标准,并得到同行认可,可以为糖尿病诊治提供可靠结果,同时也可为临床药理等研究提供有力的数据支持。 IFC...
日前,基蛋生物Getein1600参与国际临床化学和实验室医学联盟(IFCC)糖化血红蛋白(HbA1c)认证项目,获得其参考测量程序良好的追溯性,顺利通过认证!至此,基蛋生物Getein1600糖化血红蛋白产品已通过国际上在糖化血红蛋白检测领域公认的研究最早、应用最广泛的两套标准化系统——NGSP与IFCC的双重认证!何为NGSP 和 IFCC ?HbA1c的...
国际临床化学和实验室医学联盟(International Federation of Clinical Chemistry and Laboratory Medicine, IFCC)的HbA1c参考系统确保了检测系统可溯源至更高等级的参考方法以标准化HbA1c。通过这种参考系统，全球的HbA1c结果都会报告为IFCC单位(mmol/mol)和用主方程推导的NGSP单位(即总血红蛋白百分数)糖化血红蛋白的临床应用...
HbA1c检测标准化也至关重要:若HbA1c检测应用于临床,需实验室测定结果具有跨时空、跨检测系统的一致性、可比性。为此,2007年8月23日,美国糖尿病协会(ADA)、欧洲糖尿病研究协会(EASD)、国际临床化学家联合会(IFCC)以及国际糖尿病联盟(IDF)联合发布了一份统一全球糖化血...
Singh Datt G, Agarwal MM, Bishawi B. HbA1c: A comparison of NGSP wi- th IFCC transformed values. Clin Chim Acta 2005;358:81-6.Dhatt GS, Agarwal MM, Bishawi B (2005) HbA1c: a comparison of NGSP with IFCC transformed values. Clin Chim Acta 358(1–2):81–86...
HbA1c was measured on two analyzers ( n = 50). Comparability was tested by Deming regression, bias estimation and Friedman test. A strong correlation and good agreement between two methods was demonstrated. NGSP and IFCC-derived NGSP HbA1c can be used interchangeably.关键词:...
An approved IFCC reference method for measuring HbA1c, with a firm and reproducible correlation with NGSP values, is now available. We established (i) the degree of agreement of HbA1c results between the NGSP-certified and the IFCC-calibrated (converted to NGSP values) immunochemical method and ...
6) AGEs (Advanced Glycosylation End Products )最終糖化蛋白(AGEs)是引起糖尿病併發症的元兇 Monitoring Diabetes Self Monitoring Blood glucose test (SMBG) Hemoglobin A1c (HbA1c) testing Complete separation of Hb Kaoshiung QA Activity in HbA1c test in Taiwan 1.使用NGSP/IFCC認證過的檢測方法 2.Traci...
In between the IFCC and NGSP, there is a difference in HbA1c units with a master equation of NGSP%=(0.915 x IFCC%) + 2.15 (22). It is recommended that HbA1c methods have intra-laboratory %CV <2 and inter-laboratory %CV of <3.5 [22] a total error of no more than 0.5% (5mmol...
(NGSP) units) or mmol/mol (System International (SI) units used by the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) network). An HbA1cvalue of ≥6.5 % or 48 mmol/mol is used as a threshold for the diagnosis of diabetes [2]. Pre-diabetes is defined...