In the present invention, knockouts have a partial or complete loss of function in one or both alleles of the endogenous SARG-1. Knockins have an introduced transgene with altered genetic sequence and function from the endogenous gene. The two may be combined, such that the naturally occurring...
There are at least two different alleles for the gene controlling height. There is one allele for height with two different forms. There are two different genes for height, each having a single allele. A There are two different genes for height, each having a single allele. B The...
(CAPS) system to discriminate the three different alleles of the TBG4 locus. Basically, genomic DNA from plants of unknown genotype was amplified using primers TBG4F-3207 and TBG4F-3208 (SEQ ID NOs: 23 and 24). The PCR product was then digested with the restriction endonuclease BsgI. ...
The synthetic peptide TT3, the amino acid sequence of which corresponds to the region 947-967 of the tetanus toxin is recognized by different human Th cell clones in association with a wide range of alleles of the human major histocompat... E Bianchi,A Pessi,G Corradin - EP 被引量: 399...
Delhi, Delhi, India and that of the Institute of Genomics and Integrative Biology, Mall Road, Delhi-110007, India, approved the present study. Example 2 ELISA Assay for the Detection of Autoantibodies to MBL The presence of anti-MBL autoantibodies was tested for in 107 RA patients and 121 ...
Of the two alleles of the light chain gene in DT40, one is in germline configuration and is not expressed, whereas the other has undergone VJ rearrangement to express the light chain gene. The rearranged allele may be knocked out because it eliminates expression of the endogenous light chain,...
[0072] “Fragments” as used herein are a portion of a naturally occurring protein which can exist in at least two different conformations. Fragments can have the same or substantially the same amino acid sequence as the naturally occurring protein. “Substantially the same” means that an amino...
The term fusion protein refers to a chimeric protein molecule comprising two or more domains from different sources. The term DNA construct refers to genetic sequence used to transform cells. These constructs may be administered to cells in a viral or plasmid vector. The term reporter gene ref...
Fatty acid composition of the F2 seed showed the two lines to be allelic. The mutational events in M3051.10 and M3052.1 although different in origin were in the same gene.An additional M5 line, M3054.7, contained 1.0% and 1.3% stearic acid in the greenhouse and field respectively. A ten-...
All alleles receive at least a four digit name, which corresponds to the first two sets of digits, longer names are only assigned when necessary. The digits before the first colon describe the type, which often corresponds to the serological antigen carried by an allotype. The next set of ...