the Yoshino B4000 solid-state solar generator is the world's first portable power station that relies on a solid-state battery for enhanced safety. It provides 2.5x higher energy density and up to 4,000 charging cycles to 80 percent capacity. It's the ideal gift for an...
Dietary protein has a positive influence on bone mineral density in severely osteoporotic patientsMcDonald, CChan, G CToth, ZKennedy, N PWalsh, J BCasey, M C
Over the past two decades, technological advances in membrane protein structural biology have provided insight into the molecular mechanisms that transporters use to move diverse substrates across the membrane. However, the plasticity of these proteins’ ligand binding pockets, which allows them to bind...
Micro- and nanoplastics can interact with various biologically active compounds forming aggregates of which the effects have yet to be understood. To this end, it is vital to characterize these aggregates of key compounds and micro- and nanoplastics. In
The structure of Rep15:Rab3C reveals that, unlike most Rab effectors8, Rep15 is a single domain globular protein which presumably explains why the other three deletion Rep15 constructs were not soluble. No electron density was observed for the first 14 amino acids, the middle 117 to 130 amin...
energy metabolism and feeding behaviour2,4,5. Concurrently, people with aberrant insulin response have higher visceral adipose tissue mass and impaired peripheral metabolism6,7,8and regain more fat mass after a lifestyle intervention7. Furthermore, findings from numerous studies suggest that the ...
In addition to this digestive role, bile acids are now known to function as signalling molecules to regulate their own synthesis, energy metabolism, glycemic control and immunity15–20. The effects of bile acids on gene transcription are mediated by the farnesoid X receptor (FXR) that is ...
Still, the growth of wild type yeast could be inhibited by very high concentrations and long exposure at low cell density offering the opportunity to use yeast Qo-site mutants (with an unmodified Qi-site) to test for binding to the Qo-site. Note that the growth of Qi-site mutant PFQi3...
FinO-domain proteins are a widespread family of bacterial RNA-binding proteins with regulatory functions. Their target spectrum ranges from a single RNA pair, in the case of plasmid-encoded FinO, to global RNA regulons, as with enterobacterial ProQ. To a
Phosphate is one of the most abundant anions and an essential mineral for all organisms. It is required for numerous cellular functions such as cell signalling, energy transfer, metabolic pathways, regulation of protein synthesis and activity, maintenance of acid–base homeostasis and bone ...