Regional and distant stage breast cancer survival has improved markedly for high SES patients, but there has been little survival gain for low SES patients. Socioeconomic status matters for the stage-specific s
ER + /HER2 + Breast Cancer Has Different Metastatic Patterns and Better Survival Than ER /HER2 + Breast CancerCletus A. ArcieroYi GuoRenjian JiangMadhusmita BeheraRuth O'ReganLimin PengXiaoxian LiClinical Breast Cancer
When applied to a large YWBC cohort, these signatures for ER+ PPBC associate with significantly reduced 15-year survival rates in high compared to low expressing cases. Cumulatively these results provide evidence that PPBC is a unique entity within YWBC with poor prognostic phenotypes....
that higher post-diagnostic coffee consumption was associated with lower rates of breast cancer-specific death compared to no coffee intake during up to 30 years of follow up. Those drinking over three cups per day experienced a 25% lower risk of death from breast cancer compared to non-...
CPYPP Overall survival was considerably lower in patients with low mALI than in those with high mALI, a statistically significant difference (P<0.0001) reflected in survival rates of 395% versus 655%. For men, OS rates were substantially lower in the low mALI group in comparison to the high...
Thus, from these randomized trials, it appears that higher response rates can be achieved with some combination chemotherapy regimens. Toxicity is more severe, and overall survival time as measured by median survival time is not improved. However, one study did find that a significantly greater ...
(P < 0.0001 for all comparisons). The 5- and 30-year corrected survival rates of women with ILC were 78% and 50%, respectively, compared with 63% and 37% for women with IDC (P = 0.001). Small pT1NOMO ILCs (n = 41) had 100% 10-year and 83% 20-year corrected survival rates....
This signature had a prognostic value (overall survival, relapse-free survival, and distant metastasis-free survival) in breast cancer. qRT-PCR, Western blot, and immunohistochemistry analyses validated the link of three members of this signature (KIFC1, LRRC59, and TRIP13) with HMGA1 expression...
triple-negative breast cancer; AEs, adverse events; SoC, standard of care; ORR, objective response rate; CNS, central nervous system; PFS, progression-free survival; DFS, disease-free survival; pCR, pathologic complete response; IV, intravenous; LNs, lymph nodes; DCs, dendritic cells; GM-CSF...
BCMA and CD33 ADCs have demonstrated activity in diseases as prevalent as multiple myeloma and acute myeloid leukemia. Even rarer cancers, where survival rates are notoriously low due to lack of options, could see improved outcomes from precisely-targeted ADCs. Neoadjuvant and adjuvant settings pre-...