In order for a population to be in HW equilibrium, 5 conditions must be met: 1. Very large population 2. No migration 3. No net mutations 4. Random mating 5. No natural selection Therefore, … We do not really expect a natural population to be in Hardy Weinberg equilibrium ...
Hardy-Weinbergequilibrium ifp=frequencyofalleleA q=frequencyofallelea p+q=1,(p+q) 2 =1 p 2 +2pq+q 2 =1 ifonlylawofprobabilityaffectsthe frequencyw/whichgametescombine toformnewindividuals Bisexualpopulation Largepopulation Randommating
群体遗传学Hardy-Weinberg平衡定律检验作者:路文盛版本:V.0实际频数预计频数基因频率CC196187.36150.7865CT5774.76950.11896TT167.361540.05948N69C4490.83457T890.16548n538χ14.55387P0.000136结论:当P>0.05时,说明群体基因遗传平衡,数据来自同一蒙德尔群体。
The Hardy-Weinberg equilibrium is a principle stating that the genetic variation in a population will remain constant from one generation to the next in the absence of disturbing factors. When mating is random in a large population with no disruptive circumstances, the law predicts that both ...
Hardy–Weinberg equilibrium,叫做哈迪-温伯格平衡。该定律 提出,对于一个足够大的群体,在群体中各个个体之间随机交配,在 没有突变,个体迁移,遗传漂变等因素发生的情况下,这个种群的基 因频率和基因型频率可以一代代稳定不变,保持平衡。 对于二倍体生物而言,等位基因 A 的频率用 p 表示,a 的频率用 q 表示,在满...
Hardy–Weinberg equilibrium - nonparametric compositional approachHardy and Weinberg (1908), independently formulated - principle, that the genotypes at a bi-allelic locus, in proportions p2, 2pq and q2modern genetic studies - using single nucleotide polymorphisms (SNPs)...
Hardy–Weinberg equilibrium Hardy–Weinberg equilibrium,叫做哈迪-温伯格平衡。该定律提出,对于一个足够大的群体,在群体中各个个体之间随机交配,在没有突变,个体迁移,遗传漂变等因素发生的情况下,这个种群的基因频率和基因型频率可以一代代稳定不变,保持平衡。
哈迪-温伯格平衡定律(Hardy-Weinberg equilibrium,HWE)方便计算 群体遗传学HardyWeinberg平衡定律检验 作者:路文盛 版本:V2.0 实际频数预计频数基因频率 CC196 187.36150.728625 CT57 74.276950.211896 TT16 7.3615240.05948 N 269 CTn 结论:当P>0.05时,说明群体基因遗传平衡,数据来自同一蒙德尔群体。44989538 ...
应用Hardy-Weinberg遗传平衡吻合度检验方法,把计算得到的基因频率代入,计算基因型平衡频率,再乘以总人数,求得预期值(e)。把观察数(O)与预期值(e)作比较,进行χ2检验。病例组和对照组的基因型分布的观察值和预期值差异无显著性(P>0.05),符合遗传平衡定律:for example,下表为一个具体的Hardy-Weinberg遗传平衡检验...