Hand-foot syndrome (HFS) is a serious dose-limiting cutaneous toxicity of capecitabine-containing chemotherapy, leading to a deteriorated quality of life and negative impacts on chemotherapy treatment. The symptoms of HFS have been widely reported, but the precise molecular and cellular mechanisms ...
Hand foot syndrome Hand foot syndrome (HFS), or palmar-plantar erythrodysesthesia, most commonly occurs with cytotoxic agents, including 5-fluorouracil, capecitabine, cytarabine, methotrexate, docetaxel, and doxorubicin (Fig. 12-2). These drugs are believed to be transported by eccrine sweat glands...
How can one manage hand-foot syndrome and other cutaneous toxic effects of capecitabine and 5FU-based therapy, other than dose-delay or dose-reduction? Response from Harold J. Burstein, MD, PhD Hand-foot syndrome (HFS) is characterized by erythema, numbness, tingling, and either dysesthesias ...
Hand-foot syndromepalmoplantar erythrodysesthesiachemotherapycapecitabine5-fluorouracilIntroduction: Hand-foot syndrome (HFS) is a well-established cutaneous adverse event of certain chemotherapeutic agents, mainly capecitabine, continuously infused 5-fluorouracil, docetaxel and pegylated liposomal doxorubicin. ...
Unilateral hand–foot syndrome: an extraordinary side effect of capecitabine[J]. Cutaneous and Ocular Toxicology .2010(2)Unilateral hand–foot syndrome: an extraordinary side effect of capecitabine[J] . Umut Disel,Ö,zlem Gü,rkut,Hü,seyin Abal&inodot,Hakan Kalea&gbreve,as&inodot,Hü,...
Hand-foot syndrome (HFS), also known as palmar-plantar erythrodysesthesia (PPE), is a major side effect of capecitabine. Although the pathogenesis of HFS remains unknown, some studies suggested a potential involvement of inflammation in its pathogenesis. Proton pump inhibitors (PPIs) have been rep...
Palmar-plantar erythrodysesthesia (PPE), also called hand-foot syndrome or hand-to-foot syndrome, is a distinctive and relatively frequent dermatologic toxic reaction associated with certain chemotherapeutic agents. Pegylated liposomal doxorubicin (PLD), a long-circulating formulation of doxorubicin in whi...
2.指(趾)炎(dactylitis) 在幼儿病例,血管闭塞常发生于手足背,引起指(趾)炎,也称为手足综合征(hand-foot syndrome)。临床表 … www.ilinkee.com|基于15个网页 3. 手足综合症 ... ) hand-foot-genital syndrome 手足生殖器综合征 )hand-foot syndrome手足综合症) shoulder-hand syndrome 肩-手综合征 ......
Fig. 4. Decreased swelling and erythema of the bilateral hands after supportive therapy. Diagnosis: Hand-foot syndrome in patient with SSc after taxane-based chemotherapy and capecitabine. Discussion Systemic sclerosis (SSc; also known as scleroderma) is an autoimmune connective tissue disease with imm...
The agent for the prevention and/or treatment of Hand-Foot Syndrome comprising a compound with anticholinergic activity can be provided. The agent for the prevention and/or treatmen