Briefly, five to six-week-old female Golden Syrian hamsters were inoculated intranasally with 100 µL of 105 median tissue culture infectious dose of SARS-CoV-2 alpha-strain diluted with phosphate-buffered saline or a vehicle control. The infected hamsters were divided into 8 groups (n =...
Mice are typically infected as 3- to 4-week-old juveniles and because of the ubiquitous nature of the organism, virtually all mice in the 4- to 12-week-old age groups should be considered to be infected and shedding. Immunity to the organism develops rapidly, with young animals being ...