5Miscellaneous Diseases aCerebral Hemorrhage Hemorrhageoccurred in 20% of both control andexperimental animalsin a131Ichronic toxicity study, (Ward and Moore, 1969). Deaths occurred at 1–2 years of age. Grossly, thehemorrhagewas most evident between thecerebral hemispheres, with blood often in the...
Furthermore, hamsters are relatively free of pathogens yet are susceptible to several experimental infectious diseases (Valentine et al., 2012). Hamsters are used often for carcinogenesis studies; in fact, the hamster cheek-pouch carcinogenesis model is a popular model to study oral tumor formation ...
This chapter deals primarily with diseases of the Syrian hamster. Typical adenoviral inclusions have been observed only in hamsters less than 4 weeks of age. Hamsters are host to an endogenous retrovirus, which is expressed in tissues and cells as C-type particles without evidence of oncogenicity...
Some of the diet-induced effects are long lasting and can lead to various adult-based diseases. In the current studies, we examined the short-term effects of dietary cholesterol on neonatal hepatic sterol metabolism and the long-term effects that those early-life diets had on sterol metabolism ...
Skin Diseases Ringworm is a common skin disease in dwarf hamsters but problems can also develop from other allergies. Certain types of sawdust and bedding can often cause these problems, particularly cedar shavings or sawdust. Change up your bedding material if you start noticing any skin issues...
Analysis of plasma lipids of 30- and 185-day-old BIO 82.62 myopathic hamsters and age-matched normal controls revealed a decrease in only the concentration of cholesteryl esters of 185-day-old diseased animals. Measurement of lipoprotein lipase (LPL) activity in heart, muscle, and adipose tissue...
However, given that human populations over the world are diverse, this trait of hamsters is highly similar to that of human, giving hamsters a lead in precision medicine and translational research of human diseases. Eventually, the conclusions drawn from the experiments using hamsters as experimental...
Clinically, risk factors such as gender, age, and underlying diseases might be related to the severity of COVID-19. Several recent cohort studies have suggested that SARS-CoV-2 infection causes more severe lung diseases and higher mortality in male than in female.3,4,5,6 It was also found...
Osteoarthritis and degenerative joint disease are diseases that a hamster may develop in old age. These diseases are rare in hamsters under 2 years of age. The diseases are characterized by separation of the zone of calcification of the cartilage with sclerosis and dislocation of the bone, fibrill...
PVM may also be a copathogen in other respiratory diseases, such as mycoplasmal infections. Hamster PVM infection in this species normally goes undetected as a subclinical event. Animals inoculated with PVM exhibit sneezing, dyspnea, and weakness, with death ensuing 6 to 15 days post infection. ...