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A major challenge in drug discovery is the identification of high affinity lead compounds that bind a particular target protein; these leads are typically identified by high throughput screens. Mass spectrometry has become a detection method of choice in drug screening assays because the target and ...
Nathan McDonnell complained to gardaí about crime link rumours in months before €32m drug haul Oireachtas member arrested over alleged €150,000 business fraud Nathan McDonnell’s rise and fall: ‘While there is sympathy for his family, there is very little for him persona...
Case report: drug interference with MIBG uptake in a patient with metastatic paraganglioma Metaiodobenzylguanidine (MIBG) labelled with -131 ((131)I) has become a well established therapeutic tool for inoperable metastastic of . There are differe... K Zaplatnikov,C Menzel,Dbert, N,... - ...
Drug reaction monitoring yields more drug-event associations than can practically be pursued by individualized detailed study. The criteria for selecting those associations of greatest importance relate to (1) the degree of certainty as ... GD Friedman - 《Journal of Chronic Diseases》 被引量: 23...
Here, we test a set of metallodrugs and related compounds, and identify ranitidine bismuth citrate, a commonly used drug for the treatment ofinfection, as a potent anti-SARS-CoV-2 agent, both in vitro and in vivo. Ranitidine bismuth citrate exhibited low cytotoxicity and protected SARS-CoV-2...
You may know Alton Brown from his classic TV show "Good Eats," from hosting Food Network's "Cutthroat Kitchen" or for his impeccable Bow tie fashion collection. On "CBS This Morning: Saturday," the celebrity chef dished out a few of his signature recipes for you to try at home. Here'...
These results further demonstrate the usefulness of tuftsin-bearing liposomes as drug vehicles in treatment of the macrophage-based infections that have been reviewed recently (Agrawal, A.K. and Gupta, C.M. (2000). Tuftsin-bearing liposomes in treatment of macrophage-based infections, Adv. Drug...
(Amp B), which is the drug of choice for treatment of the leishmanial infections (kala-azar) that become resistant to the conventional chemotherapy using antimonials, has been examined in the Leishmania donovani infected hamsters after encapsulating the drug in tuftsin-free as well as tuftsin-...
These observations suggest that the prolongation of survival by appropriately timed treatment with this T cell directed drug model is caused by the inhibition of humoral as well as cellular xenograft rejection.Masashi TsugitaLuis A. ValdiviaAbdul S. Rao...