TriazolamAdministration, OralHalf-LifeMaleStatistics as TopicNo abstract is available for this article.doi:10.1002/j.1552-4604.1989.tb03395.xDavid J. GreenblattDivision of Clinical Pharmacology, Departments of Psychiatry and Medicine, Tufts University School of Medicine and New England Medical Center, ...
Alprazolam andtriazolam, containing a fused triazolo ring, undergo α-hydroxylation on themethyl groupof the ring. This reaction is mediated through hepaticCYP3A4isoenzymes, and the subsequent conversion to theglucuronideoccurs rapidly in the case of triazolam and accounts for the short duration of ...
Semi-micro column HPLC of triazolam in rat plasma and brain microdialysate and its application to drug interaction study with itraconazole Also, the AUC of TZ in plasma increased 2.6-folds and remarkable delay in its elimination half-life ( t 1/2) was observed. The concentrations of TZ... ...
Within a double-blind, comparative study on the effects of the long-half-life benzodiazepine (BDZ), quazepam, and the short-half-life BDZ, triazolam, on cl... B Saletu,P Anderer,Brandstä,... - 《Neuropsychobiology》 被引量: 121发表: 1994年 Longer-acting factor VIII to overcome li...
Various drugs including amphetamine, methamphetamine, MDMA, MDA, benzodiazepines, or metabolites (nordiazepam, oxazepam, temazepam, alprazolam, alpha-OH alprazolam, bromazepam, lorazepam, triazolam, alpha-OH-triazolam, desalkyl-flurazepam, clonazepam, 7-amino clonazepam), cannabinoids (confirmed as THC-CO...
Method and laminated composite for administering short or intermediate half-life benzodiazepines such as alprazolam or triazolam transdermally to treat conditions such as anxiety in the case of alprazolam and insomnia in the case of triazolam. The composite comprises an impermeable backing layer and a ...
Half-LifeAdultThe effect of time of day of drug administration on triazolam pharmacokinetics was studied in ten healthy men. In a randomized, two-way, ... RB Smith,PD Kroboth,JP Phillips - 《Journal of Clinical Pharmacology》 被引量: 28发表: 2013年 ...
Effect of grapefruit juice dose on grapefruit juice-triazolam interaction: repeated consumption prolongs triazolam half-life. Eur J Clin Pharmacol 2000;56:411-5.Lilja JJ, Kivisto KT, Backman JT, Neuvonen PJ. Effect of grapefruit juice dose on grapefruit juice-triazolam interaction: repeated ...
Method and laminated composite for administering short or intermediate half-life benzodiazepines such as alprazolam or triazolam transdermally to treat conditions such as anxiety in the case of alprazolam and insomnia in the case of triazolam. The composite comprises an impermeable backing layer and a ...
composite laminate and process for administration of benzodiazepines with short half lives, such as the alprazolamine intermediate or triazolam transdermally to treat conditions such as anxiety, in the case of alprazolam and not in the case of the tria zolam.the composite (10) comprises a backing...