Alprazolam and triazolam, containing a fused triazolo ring, undergo α-hydroxylation on the methyl group of the ring. This reaction is mediated through hepatic CYP3A4 isoenzymes, and the subsequent conversion to the glucuronide occurs rapidly in the case of triazolam and accounts for the short dur...
Rebound insomnia and elimination half-life: assessment of individual subject response. J Clin Pharmacol. 1985;25:115.Bixler EO, Kales JD, Kales A, et al : Rebound insomnia and elimination half-life: assessment of individual subject response. J Clin Pharmacol ; in press....
Effect of grapefruit juice dose on grapefruit juice-triazolam interaction: repeated consumption prolongs triazolam half-life. Eur J Clin Pharmacol 2000; 56: 411-5.Lilja JJ, Kivisto KT, Backman JT, Neuvonen PJ. Effect of grapefruit juice dose on grapefruit juice – triazolam interaction: ...
Classification of Half-life: The term "half-life" refers to the time it takes for a specific isotope's radioactivity to reduce by half from the original value. This term is often used for metals such as zinc or copper. Answer and Explanation: The half-life ...
composite laminate and process for administration of benzodiazepines with short half lives, such as the alprazolamine intermediate or triazolam transdermally to treat conditions such as anxiety, in the case of alprazolam and not in the case of the tria zolam.the composite (10) comprises a backing...
Method and laminated composite for administering short or intermediate half-life benzodiazepines such as alprazolam or triazolam transdermally to treat conditions such as anxiety in the case of alprazolam and insomnia in the case of triazolam. The composite comprises an impermeable backing layer and a ...
Method and laminated composite for administering short or intermediate half-life benzodiazepines such as alprazolamine or triazolam transdermally to treat conditions such as anxiety in the case of alprazolam and insomnia in the case of triazolam. The composite comprises an impermeable backing layer and ...
50% more car crashes in elderly users of long half-life benzodiazepinesAlprazolamTriazolamOxazepamElderly UserNitrazepamNo Abstract available for this article.doi:10.2165/00128415-199706590-00009NoneSpringer International PublishingReactions WeeklyNA;. (1997) Inhaled corticosteroids increase risk of cataracts. ...
Method and laminated composite for administering short or intermediate half-life benzodiazepines such as alprazolam or triazolam transdermally to treat conditions such as anxiety in the case of alprazolam and insomnia in the case of triazolam. The composite comprises an impermeable backing layer and a ...
2115841 9303694 PCTABS00020 Method and laminated composite for administering short or intermediate half-life benzodiazepines such as alprazolamine or triazolam transdermally to treat conditions such as anxiety in the case of alprazolam and insomnia in the case of triazolam. The composite (10) comprises...