Growth and differentiation of postnatal hair follicles are controlled by reciprocal interactions between the dermal papilla and the surrounding epidermal h... Kulessa,H. - 《Embo Journal》 被引量: 135发表: 2014年 Human hair follicle regeneration following amputation and grafting into the nude mouse....
The base of the hair follicle is deep within the dermal tissue, the hair follicle itself is anchored to the skin by arrector pili muscles and sebaceous glands. Hair follicles have large numbers of sensory fibers that circumferentially wrap around the base of the follicle and extend up the ...
Hair follicles and dermal adipose tissue (dWAT) are two major components of mammalian skin, each with its distinct anatomy and cellular lineage. Yet, in late embryogenesis they come in direct contact and become physiologically coupled in adulthood into a remodelling cycle. Indeed, in species, ...
Hair regenerative medicine has emerged as a promising approach for the treatment of severe hair loss. Recent advances in three-dimensional tissue engineering, such as formation of hair follicle germs (HFGs), have considerably improved hair regeneration after transplantation in animal models. Here, we ...
The rapid proliferation observed in the lower portion of the anagen whisker follicles of the rat resulted in the idea that within the matrix, the stem cells give rise to their progeny, transient amplifying cells (Ibrahim and Wright, 1982;Oshima et al, 2001). This implied that the cells ...
between external factors and metabolite changes are not fully understood. As a result, it is critical to investigate the expression of metabolites in cashmere goat hair follicles/skin tissues in all three stages, and this is an important part of research on the regulatory mechanism of hair growth...
Dermal cells from mice or rats are also able to induce human foreskin keratinocytes to form hair follicle-like struc tures12, but formation of human hair follicles by combining cultured postnatal human dermal and epidermal cells has not been achieved13. TSC is caused by mutations of a ...
The HFSC niche is composed of various component cells, such as dermal papilla, preadipocytes, adipocytes, immune cells and nerves. Systemic hormones also regulate HFSCs directly or indirectly through the HFSC niche cells. Both activating and suppressive signals are present within the HFSC niche. ...
The hair follicles are downgrowths of the epidermis in which an ordered array of keratinized cells is gradually pushed upward in the form of hair shafts. From:Fundamentals of Toxicologic Pathology (Second Edition),2010 About this page Set alert ...
Hair follicles are epidermal invaginations that project into the dermis (Fig. 3.2). The proximal tip of the follicle is invaginated to form a cap over the dermal papilla, a condensation of dermal fibroblasts associated with the follicle (Hardy, 1992). This cap is called the matrix, and its...