18. Beier C, Kaufmann R. Efficacy of erbium:YAG laser ablation inDarier disease and HaileyeHailey disease. Arch Dermatol.1999;135:423-427. 19. Downs A. Smoothbeam laser treatment may help improvehidradenitis suppurativa but not HaileyeHailey disease.JCosmet ...
Hailey-Hailey病(Hailey-Hailey disease, HHD)是一种罕见疾病,又称慢性家族性良性天疱疮,好发于20-40 岁人群,发病率约为1/50,000,表现为对称分布于间擦部位(腹股沟、腋窝、颈部、乳房下区及会阴)的水疱、糜烂、浸渍和频繁的继发感...
inflammatory skin diseasemonoclonal antibodyrecalcitrant skin conditionskin barrier dysfunctiontargeted biologic therapydoi:10.1016/j.jdcr.2024.09.030Deep PatelDepartment of Dermatology, Medical College of Wisconsin, Milwaukee, WisconsinJason RosenbergAscension Columbia St. Mary’s Hospital, Milwaukee, Wisconsin...
Control of hyperhidrosis, which aggravates familial benign pemphigus (Hailey-Hailey disease), may be the mechanism for this off-label, novel approach. Remissions of up to at least 12 months have been achieved using only botulinum A toxin injection. Only a few isolated reports have been published...
Progress has been made in the treatment of this disease through the persistent use of cortisone, administered orally, and of the pituitary extract ACTH, administered intramuscularly. Fatalities, once fairly common, now can usually be averted. The disease is difficult to control, however, and ...
Achieving stable and long‐term disease control is challenging with currently available conventional treatment options.3 Botulinum toxin type A is an alternative treatment option to consider in all cases of Hailey–Hailey. Botulinum toxin type A reduces sweating in the intertriginous areas, thereby ...
Hailey-Hailey disease (HHD) or chronic benign familial pemphigus is an autosomal dominant genodermatosis with complete penetrance characterized by painful vesicles, erosions, and macerated intertriginous skin. We present a 66-year-old woman with a personal 35-year history of pruritic recurrent ...
DISCUSSION The prevalence of Hailey–Hailey disease (HHD) also known as familial benign chronic pemphigus is 1:50,000.[1] It is an autosomal dominant disorder caused due to mutation in ATP2C1 gene.[2 3] The gene encodes an adenosine tripho
Osler–Rendu–Weber disease (hereditary haemorrhagic telangiectasia; HHT) An autosomal-dominant disorder where telangiectases are present orally, periorally and in the nose, gastrointestinal tract and occasionally on the palms. Telangiectases may bleed, and cryosurgery or laser treatment may be nee...
D., Darier–White disease: a review of the clinical features in 163 patients, J Am Acad Dermatol, 1992, 27(1):40–50. [4] BURGE S. M., Hailey–Hailey disease: the clinical features, response to treatment and prognosis, Br J Dermatol, 1992, 126(3):275–282. [5] ...