Haemoglobin levels were measured preoperatively, postoperatively in the recovery room, and on days one, three and five after surgery. Results The mean postoperative haemoglobin concentration was 9·87 g/dl in the restrictive group and 11·09 g/dl in the liberal group. In the restrictive group...
rate, and reduced intracranial pressure along with maintenance of proper potassium levels at a well-tolerated wide range dose, further supporting its clinical development [237]. Multiple therapeutic benefits of PPHb prepared from bovine PEG-Hb are observed in three indications 1) Traumatic brain ...
An investigation into the vaccine potential of HpuAB revealed that sequences of both proteins from a range of Neisseria species are under strong immune selection25. Some homology exists between HpuAB and the other bipartite iron receptors of Neisseria, the transferrin receptor TbpAB and lactoferrin ...
Haemoglobin has a maximum theoretical oxygen-carrying capacity of 1.39 ml O2 g−1 Hb (known as Hüfner's constant), and therefore, a theoretical maximum oxygen capacity of 20.85 ml O2 100 ml−1 blood at a ‘normal’ haemoglobin concentration of 15 g dl−1 (range 13.5–18.0 in men,...
range of maximum physiological tolerance (Δp50 between rest and VO2max: 8–10 mmHg). Individual baseline Hb-O2affinity, therefore, is of huge importance. At rest, 2,3-BPG determinates the baseline p50 in healthy subjects, because of its strong correlation and the finding that pCO2levels ...
The spread of CV values was also higher for results from faecal-like matrix schemes with an interquartile range (IQR) 4.4–24.0% vs. liquid IQR range of 0.3–2.5%. Conclusions Hb results from faecal-like matrices, whilst more aligned to a patient or participant sample, are prone to pre...
Fetal haemoglobin (HbF) levels have a clinically beneficial effect on sickle cell disease (SCD). Patients with SCD demonstrate extreme variability in HbF levels (1–30%), a large part of which is likely genetically determined. The main genetic modifier loci for HbF persistence, HBS1L-MYB, BCL...
(PPIX)L2] complexes are in the range 555–564 nm and those for [Fe(II)(PPIX)L(CO)] complexes are in the range 562–574 nm. In total contrast, the bands in the [Fe(II)TPPS)L2] complexes are in a tight range from 562 to 566 nm while those for the [Fe(II)(TPPS)L(CO)] ...
the line inside the box is the median and whiskers represent the ±1.5 times the interquartile range. EPO serum levels are plotted on the log-scaledy-axis. The median value of serum EPO concentration of carriers was 3.23-fold higher (median = 22.1 IU L−1; Q1 = 14.1;...
Oke JL, Stevens RJ, Gaitskell K, Farmer AJ. Establishing an evidence base for frequency of monitoring glycated haemoglobin levels in patients with Type 2 diabetes: projections of effectiveness from a regression model. Diabet Med. 2012 Feb;29(2):266-71....