HAE attacks can occur suddenly and without warning. However, many people notice symptoms at the very early stages of an attack, including sudden mood change, irritability, extreme fatigue, nausea, rash or tingl
The excess of bradykinin triggers attack-like swellings (angioedema) of the skin and/or mucous membranes. Depending on the swellings' location, they can lead to functional impairment and can be disfiguring, painful, or life-threatening. Patients with HAE have significantly impaired quality of ...
While there’s no way to predict when an HAE attack will occur, some people report symptoms that seem to signal an attack is near. Others are able to identify certain triggers, such as stress, an infection, or medication, that spark an episode. It’s a good idea to keep a journal li...