As such, they represent a unique opportunity to approximate the microbiota-host configura- tions arising from a foraging subsistence strategy, similar to that of ancient humans, which has accompanied over 90% of our evolutionary history9. In order to account for the contribution of intestinal ...
This is especially problematic because humans have relied on hunting and gathering for 95% of our evolutionary history. Here, to explore how a foraging subsistence strategy influences GM profiles, we analyse faecal microbiota from 27 Hadza hunter- gatherers from two separate camp sites (Fig. 1)....
Many genomes recovered from the Hadza come from species that are absent from the Unified Human Gastrointestinal Genome (UHGG) database19 and the Metagenomic Gut Virus (MGV) catalog33 (20.2% and 79.9%, respectively) (Figures 2A and 2B). MAGs recovered from the Hadza expand the UHGG, v1 dat...