The emergence and spread of highly pathogenic avian influenza (HPAI) strains, such as H5N1, have raised concerns due to their potential to cause severe outbreaks and cross the species barrier, leading to human infections and global public health emergencies. In this study, we repo...
近日, 廖明教授 / 代曼曼副教授课题组在在国际知名期刊PLOS pathogens在线发表了题为“Dissection of key factors correlating with H5N1 avian influenza virus driven inflammatory lung injury of chicken identified by single-cell analysis”的研究论文 ,揭示了H5N1 禽 流感病毒感染诱导鸡免疫损伤的关键宿主因子。 目...
The study found the currently circulating H5N1 virus emerged in the Netherlands in October 2020 as an H5N8 avian influenza-virus recombination with subtypes such as H1N1 and H3N8. The H5N1 virus was responsible for the loss of over 70 million domestic poultry in Europe, Africa, Asia, and North...
Avian influenza virus pathogens continuously pose challenges to animal and human health. The dynamic nature of AI viruses suggests that the emergence of a pandemic-causing virus makes isolation an unlikely containment measure [11]. This study aimed to ascertain the collective occurrence of the H5N1 ...
Avian influenza has been regarded as a human health threat. A major measure to prevent its outbreak is vaccination. In this study, a series of expression p... Q Chen,H Kuang,H Wang,... - 《Virus Genes》 被引量: 85发表: 2009年 Is avian influenza virus A(H5N1) a real threat to hu...
Towards control of avian influenza H5N1 virus in Indonesia: Human infection, and the role of live bird markets. Indonesia has been heavily affected by the emerging avian influenza (AI) H5N1 virus, with continued outbreaks in farmed birds and periodic detection of human cases. The epidemiology of...
The serologic data obtained as part of the epidemiologic study of the initial case support the preliminary conclusion that persons with high levels of exposure to infected poultry or direct exposure to the virus in the laboratory may be at increased risk for infection with influenza A(H5N1) virus...
Table 1 North American HPAI A(H5N1) clade 2.3.4.4b viruses used in this study Full size table Fig. 1: Pathogenicity of North American HPAI Influenza A(H5N1) clade 2.3.4.4b Wigeon/SC/21 and Eagle/FL/22 viruses in ferrets. A Experimental design of ferret pathogenesis and transmission. At...
Highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b viruses were first detected in St. John’s, Canada in late 2021. To investigate the patterns of avian influenza virus (AIV) infection and immune responses subsequent to the arrival of H5N1, we
WHO announced that among these avian influenza viruses, H5N1 and H7N9 demand further surveillance [5]. Both H5N1 and H7N9 viruses can cause lethal infections, with mortality correlating with a wider distribution of viral antigen, mainly in the lungs, as well as other organs in the body...