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Similarly, mushroom growers in Chester County were short 1,000 longtime Mexican seasonal workers, because they couldn't obtain H2A visas for temporary work. Mexico has a strategy to deal with Trump's wall Emmanuel Geslani, a long-time recruitment and migration expert, said that H2A visas are ...
Hypoxia plays an important role in the chemotherapy resistance of nasopharyngeal carcinoma (NPC). Ferroptosis is a newly discovered form of programmed cell death and ferroptosis inducers showed promising therapeutic effects in some cancers. However, the
Lewis BP, Green RE, Brenner SE (2003) Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans. Proc Natl Acad Sci 100(1):189–192 ArticleCAS Li M, Collins R, Jiao Y et al (2011) Somatic mutations in the transcriptional corepressor gene BCORL...
We would like to thank Dr Didier Trouche for the Tip60 expressing vector and insightful discussions, J Eeckhoute, Lille for sharing unpublished work, and David Laperriere, IRIC, Montreal, for expert advice on genome database use. This work was supported by the Ligue Nationale Contre le Cancer...
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. ...
In these tumours, open chromatin emerged at transcription start sites where H2A.Z was lost, which was associated with upregulation of genes. Furthermore, YEATS4 defects were associated with abnormal upregulation of bivalent embryonic stem cell genes, as previously shown in mice5. Our work ...
Interactions between chromatin-associated proteins and the histone landscape play major roles in dictating genome topology and gene expression. Cancer-specific fusion oncoproteins, which display unique chromatin localization patterns, often lack classica
means of a domain that shares no sequence homology to any known kinase fold. We show that WSTF phosphorylates Tyr 142 of H2A.X, and that WSTF activity has an important role in regulating several events that are critical for the DNA damage response. Our work demonstrates a new mechanism that...
In this work, we show that macroH2A2 is a negative regulator of self-renewal in glioblastoma stem cells, and repression of macroH2A2 abrogates cellular transitions from proneural to mesenchymal/astrocytic cellular states. Results Low expression of MACROH2A2 is a negative prognostic factor for GBM ...