DNA damage, caused by ionizing radiation, UV-light, or radiomimetic agents, results in rapid phosphorylation of H2A.X at Ser139 by PI3K-like kinases, including ATM, ATR, and DNA-PK (2,3). Within minutes following DNA damage, H2A.X is phosphorylated at Ser139 at sites of ...
DNA damage, caused by ionizing radiation, UV-light, or radiomimetic agents, results in rapid phosphorylation of H2A.X at Ser139 by PI3K-like kinases, including ATM, ATR, and DNA-PK (2,3). Within minutes following DNA damage, H2A.X is phosphorylated at Ser139 at sites of DNA damage to...
Studies have shown that many tumor cells under a hypoxic microenvironment are less sensitive to chemotherapeutic agents because these agents typically require oxygen for maximum activity [12]. Regardless of oxygen concentrations required for anticancer drug activity, researches have also revealed that the ...
bioAgents | vitalquan | UmanDiagnostics | Toxin Technologies | taiclone | unitedchem | schebo biotech | schircks laboratories | Scimedx | SCICONS | scientech corp | SSI Diagnostica | synabs | Simicon | somru bioscience | sierra bioresearch | rna medical | RIKEN | RELIATech | pfaltzand&...
bioAgents | vitalquan | UmanDiagnostics | Toxin Technologies | taiclone | unitedchem | schebo biotech | schircks laboratories | Scimedx | SCICONS | scientech corp | SSI Diagnostica | synabs | Simicon | somru bioscience | sierra bioresearch | rna medical | RIKEN | RELIATech | pfaltzand&...
Post-Translational Modification: Phosphorylated on Ser-140 (to form gamma-H2AX or H2AX139ph) in response to DNA double strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks, and may also occur during meiotic recombination events and immunoglobulin class switchi...
Eurofins Technologies Hungary Kft H2AFLA 产品说明书 MATERIAL SAFETY DATA SHEET EUROFINS TECHNOLOGIES ELISA KITS H2AFLA – HU0040055 / HU0040054 1. Identification of the substance/preparation and of the Company/Undertaking 1.1 Product identifiers Product name H2AFLA – HU0040055/ HU0040054 1. ...
Upstate offers a rapid and sensitive microplate-based assay for the detection of H2A.X phosphorylation. Histone H2A.X phosphorylation is a very rapid response to DNA damage, occurring within minutes of exposure to ionizing radiation and other agents that cause DNA double strand breaks, including apo...
Post-Translational Modification:Phosphorylated on Ser-140 (to form gamma-H2AX or H2AX139ph) in response to DNA double strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks, and may also occur during meiotic recombination events and immunoglobulin class switching...
(1). DNA damage, caused by ionizing radiation, UV-light, or radiomimetic agents, results in rapid phosphorylation of H2A.X at Ser139 by PI3K-like kinases, including ATM, ATR, and DNA-PK (2,3). Within minutes following DNA damage, H2A.X is phosphorylated at Ser139 at sites of DNA...