h-phosphonate 亚磷酸酯 更新时间:2024年12月08日 综合排序 人气排序 价格 - 确定 所有地区 实力供应商 已核验企业 在线交易 安心购 查看详情 ￥1.00/千克 湖北武汉 使用广泛 亚磷酸三苯酯 101-02-0 支持拿样 媒染剂氧化剂 长期现货 吉业升品牌 武汉吉业升化工有限公司 3年 查看详情 ￥1.00/千克 ...
Nucleoside H-phosphonates seem to be the most attractive candidates as starting materials in the chemical synthesis of DNA and RNA fragments. The 5’-hydrogen phosphonate-3’-azido-2’,3’-dideoxythimidine is one of the most significant anti-HIV prodrug, which is currently in clinical trials....
0 chemistry and application of h-phosphonates is an excellent source for those planning the synthesis of new phosphorus-containing compounds and in particular derivatives containing a phosphonate, phosphoramide or phosphonic acid diester group. the rich chemistry, low cost and easy availability of ...
Nucleoside H-Phosphonates. 15. Preparation of Nucleoside H-Phosphonothioate Monoesters from the Corresponding Nucleoside H-Phosphonates Zain et al., " Nucleoside H-Phosphonates. 15. Preparation of Nucleoside H-Phosphonate Monoesters from the Corresponding Nucleoside H-Phosphonates, " J. ... R ...
A simple and efficient protocol for the preparation of unprotected nucleoside 5'-H-phosphonates and nucleoside 5'-H-phosphonothioates via a one-step deprotection of suitable precursors with methylamine has been developed. The synthetic utility of the unprotected nucleotide derivatives was demonstrated ...
regioselective C-H borylation to afford the corresponding meta-phosphonate substituted arylboronic esters as the sole product; the resulting boronic esters were used as nucleophilic reagents in a subsequent palladium-catalyzed Suzuki–Miyaura cross-coupling to generate a range of biarylmonophosphonates. Gra...
s叙述了为他们的反华(改装)病毒活动(图5),即6-[2-(phosphonomethoxy)乙]-2,4__LW_AT__-diaminopyrimidines[例如,(R)-hpmpo-dapy、pmeo-dapy,(R)-pmpo-dapy、和5-取代pmeo-dapys ,deoxythreosyl diethyl phosphonate含有][例如pmdta和pmdtt(98)〕、和类analogs来自cidofovir[例如,(S)-hpmp-5-azac...
United States Patent US8889657 Note: If you have problems viewing the PDF, please make sure you have the latest version ofAdobe Acrobat. Back to full text
A new method for the synthesis of N-dimethoxytritylated aminoalkyl H-phosphonate monoesters is described. It consists of transesterification of diphenyl H-phosphonate with an amino alcohol, hydrolysis of the produced di(aminoalkyl) H-phosphonate diester to the corresponding monoester, followed by its ...
This study describes the synthesis and characterization of polymer complexes constructed from the radioprotective agent S-2(3-aminopropylamino) ethylphosphorothioic acid dihydrate (amifostine or WR-2721), applied in the radiation cancer treatment, and biodegradable poly(oxyethylene H-phosphonate), poly(...