Focal excrescenses of altered basement membrane material, known as corneal guttata, are a common occurrence in the elderly. A small proportion of those who develop this condition exhibit signs of corneal endothelial dysfunction and progress to Fuchs' corneal endothelial dystrophy. The relationship ...
The parameters of the endothelial cells comprising mean cell area, the proportion of hexagonal cells, and the coefficient of variation, were almost within normal limits except for 1 eye of a 79-year-old man who was speculated to be at an early stage of Fuchs endothelial corneal dystrophy. ...
The youngest of these three subjects had also a Fuchs'' endo-epithelial dystrophy in the left eye. Moreover, one of her daughters (fourth generation), a 13-year-old girl, showed an endothelial microcystic degeneration of the cornea. The relationship between the three corneal anomalies is ...
Purpose : Fuchs' Endothelial Dystrophy (FED) is the primary reason for corneal transplantation. Diagnosis involves identifying irregular microstructures on the Descemet membrane, referred to as guttata, which play a role in triggering apoptosis in corneal endothelial cells (CECs). Understanding guttata-...
The youngest of these three subjects had also a Fuchs' endo-epithelial dystrophy in the left eye. Moreover, one of her daughters (fourth generation), a 13-year-old girl, showed an endothelial microcystic degeneration of the cornea. The relationship between the three corneal anomalies is ...
Fuchs endothelial dystrophySpecular microscopyTo describe the prevalence and the corneal endotheliums morphology in Hispanic patients with primary corneal guttata (PCG).Retrospective comparative study of PCG and healthy individuals.122 (17.38%) PCG out of 702 eyes from 356 healthy patients with no ...
Purpose : To characterize corneal endothelial cell density (ECD), the proportion of low ECD, cornea guttata (CG), Fuchs endothelial corneal dystrophy (FECD), and the estimated annual rate of ECD loss in Mexican patients scheduled for cataract surgery. Methods : A prospective, cross-sectional, ...
Fuchs’ endothelial corneal dystrophyThis is a large cross-sectional, population-based survey to investigate the prevalence of central corneal guttata in the Thai population. Two communities in the central region of Thailand are (1) Phanat Nikhom district, Chonburi, and (2) Khlong Toey district,...
Descemetorhexis Without Transplantation for Guttata Predominant Fuchs DystrophyGregory Moloney
Purpose To determine whether excimer laser ablation of guttae is a viable strategy for removal of diseased tissue in Fuchs' endothelial corneal dystrophy (FECD) on excised human Descemet membranes and whether an excimer laser-created wound on healthy human corneas ex vivo is recolonized with ...