Fungal flora has an auxiliary effect on inflammatory response, metabolic disorders, and bacterial microbial regulation and host defense, while alcohol abuse causes an imbalance in the microflora of human gut as the feed-back. After alcohol stimulation, the metabolites of gut microbiota will change, ...
Inflammation is a common feature of both obesity and cancer; however, the origin of this inflammation has been largely debated. Over the past decade, growing evidence has shown that the composition of the gut microbiota and its activity might be associated not only with the onset of inflammation...
The crosstalk of gut microbiota and chronic kidney disease: role of inflammation, proteinuria, hypertension, and diabetes mellitus. Int Urol Nephrol. 2018;50:1453–66. Yang T, Santisteban MM, Rodriguez V, Li E, Ahmari N, Carvajal JM, et al. Gut dysbiosis is linked to hypertension. ...
系统标签: gut microbiota obesity metabolic inflammation disease REVIEWOpenAccessImpactofthegutmicrobiotaoninflammation,obesity,andmetabolicdiseaseClaireL.Boulangé1,AnaLuisaNeves2,JulienChilloux2,JeremyK.Nicholson1,2*andMarc-EmmanuelDumas2*AbstractThehumangutharborsmorethan100trillionmicrobialcells,whichhaveanessent...
近日,来自美国爱荷华大学病理学系研究者们在GUT MICROBES杂志上发表了题为“Dietary Isoflavones Alter Gut Microbiota and Lipopolysaccharide Biosynthesis to Reduce Inflammation”的文章,该研究发现富含异黄酮类的饮食可以特异性地调节肠道微生物区系内毒素的生物合成,从而产生抗炎反应,并降低疾病的严重程度。
论文题目“肠道菌群增加肥胖/糖尿病小鼠和人类肠道通透性和炎症的一种机制”(A mechanism by which gut microbiota elevates permeability and inflammation in obese/diabetic mice and human gut),这篇论文发表在英国胃肠病学会(British Society of Gastroenterology,BSG)的官方期刊《肠道》(Gut)春季版杂志上。
Recently, the deregulation of symbiotic host-microbe interactions in early life has been shown to alter the maturation of the immune system, predisposing the host to gut barrier dysfunction and inflammation. The main goal of this study is to decipher the role of the early-life gut microbiota-...
1.Rooks MG, Garrett WS: Gut microbiota, metabolites and host immunity. Nat Rev Immunol 2016, 16:341-352. 肠道菌群的组分 肠道菌群很多自身组分(如LPS、鞭毛蛋白、肽聚糖、甲酰基多肽以及特殊的核酸等)都可调控机体的免疫反应。例如(如上图所示),肠道拟杆菌的成分PSA经过DC细胞提呈后,诱导Treg细胞产生,同时...
R. The impact of diet and lifestyle on gut microbiota and human health. Nutrients 7, 17–44 (2015). Article CAS Google Scholar Agus, A. et al. Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation. ...
Reactive oxygen species (ROS) play vital roles in intestinal inflammation. Therefore, eliminating ROS in the inflammatory site by antioxidant enzymes such as catalase and superoxide dismutase may effectively curb inflammatory bowel disease (IBD). Here, E