The gut microbiome is a key player in the immunomodulatory and protumorigenic microenvironment during colorectal cancer (CRC), as different gut-derived bacteria can induce tumour growth. However, the crosstalk between the gut microbiome and the host in r
To uncover the source of this metabolism, we developed a multi-omics workflow combining gut microbiome metagenomics, metatranscriptomics and metabolomics from the longitudinal IBDMDB cohort of 132 controls and patients with IBD. This associated 12 previously uncharacterized microbial acetyltransferases with 5...
Existing research has found that changes in the gut microbiome can have a significant impact in areas such ascoronary heart disease,colorectal cancer, andinflammatory bowel disease. In the current study, researchers enrolled 612 test subjects between the ages of 65 and 79 years from five different ...
Tender joint count: Five RCTs reported analyzable data on tender joint counts. The heterogeneity test indicated that the heterogeneity among the included RCTs was high (I2=94%,P<0.00001). The results of meta-analysis showed that there was no significant difference in tender joint counts between...
microbiomes. Intriguingly, when assessing the degree of long-term AH1206 colonization among female and male volunteers, we identified gender-related differences in the level of strain persistence. Indeed, at the persistence test time-point (around 200 days of follow-up), the average relative ...
and recognizes UCC and APC Microbiome Ireland as leading institutions in the microbiome and brain health research. This research aligns with our UCC Futures Framework and the strategic plan for the University in the areas of Food, Microbiome, and Health and the soon-to-be-launched Future Ageing ...
MicrobiomeIntestinal16S ribosomal RNA(rRNA)sequencingBackground:Osteoporosis(OP)has become a major public health issue,threatening the bone health of middle-aged and elderly people from all around the world.Changes in the gut microbiota(GM)are correlated with the maintenance of bone mass and bone ...
The APC Microbiome Institute is a research centre funded by Science Foundation Ireland (SFI). Availability of data and materials Data is available through http://www.ebi.ac.uk/ena/data/view/PRJEB17678 with project accession # PRJEB17678 Authors’ contributions DGB was involved in study design,...
Microbiome 5, 147 (2016). CAS Google Scholar Download references Acknowledgements This publication has in part emanated from research conducted with the financial support of AIRC Foundation for Cancer Research (AIRC IG grant number 18599, MFAG grant number 23681) and Science Foundation Ireland (...
The ISS rodent habitat has provided crucial insights into the impact of spaceflight on mammals, inducing symptoms characteristic of liver disease, insulin resistance, osteopenia, and myopathy. Although these physiological responses can involve the microbiome on Earth, host-microbiota interactions during spac...