20), we calculated the Spearman correlation betweenB. vulgatusand these two VA-producing microbes (probiotics) and found that the relative abundance ofB. vulgatuswas negatively associated with both theOscillibacter valericigenes(γ = −0.41,p-value = 2.2 ×...
KetoB, produced byLactobacillusspp.4, has been suggested to exert anti-inflammatory effects30; however, previous studies have not investigated the impact of KetoB on host metabolic homeostasis. Our comprehensive quantitative analysis of LCFA-derived metabolites demonstrated, for the first time, the pot...
To learn more about incorporating both probiotics and prebiotic foods into your diet, read neurologist Dr. David Perlmutter’s cutting-edge bookBrain Maker: The Power of Gut Microbes to Heal and Protect Your Brain for Life. 5. Play in the Dirt Not all beneficial bacteria enter by way of you...
Where Ε[Ns] is the expected number of detectable microbes, and B(xi) is the probability of microbe i’s reaction being detected with an absolute population of size xi. How can we construct B(xi)? In statistical terms, B(xi) is equivalent to the power (the probability of deciding there...
and its unique enriched gut microbes. Furthermore, we establishLactobacillusas a powerful driver of human health and add significant literature support for its potential as an antioxidant. These data also suggest that the gut microbiota, in addition to its intrinsically encoded specific biocatalytic act...
Toll-like receptors (TLRs) play an important role in the innate immune system via recognizing microbes-derived pathogens and initiating the inflammatory process. TLRs have also been found in the brain, especially in the microglia, and have been indicated in the development of AD. In this review...
The widespread usage of antimicrobials has driven the evolution of resistance in pathogenic microbes, both increased prevalence of antimicrobial resistance genes (ARGs) and their spread across species by horizontal gene transfer (HGT). However, the impac
[13,14] and that the gut reports to the brain via the N. vagus and hormones about energy uptake and other conditions that might affect mood and general well-being [15]. The details of how the gut has an impact on health in general have been reviewed in detail elsewhere [1,11–15] ...
Lgr5+ intestinal stem cells (ISCs) reside within specialized niches at the crypt base and harbor self-renewal and differentiation capacities. ISCs in the crypt base are sustained by their surrounding niche for precise modulation of self-renewal and diffe
Similarly, while various steps were taken to minimise the potential effect of exposure to oxygen and environmental microbes (see “Methods”), it is possible that the microbial composition of faecal matter was altered by these factors. Considering the two populations inhabit different areas at least...