A. Foster, Gut brain axis: diet microbiota interactions and implications for modulation of anxiety and depression, Curr. Opin. Biotechnol. , 2015, 32 , 35–41 .Luna, R.A.; Foster, J.A. Gut Brain Axis: Diet Microbiota Interactions and Implications for Modulation of Anxiety ...
该小肽通过靶向“菌肠脑轴”（microbiota-gut-brain axis），刺激肠道上皮细胞产生更多厌食激素（尿鸟苷素，UGN），并促进下丘脑中具有抑食效应的POMC神经元活动增强，降低动物摄食量；此外，该小肽还可以显著改善肠道菌群平衡，提高嗜黏蛋白阿克曼氏菌(Akkermansia muciniphila)丰度。首先，研究人员从人体体液防御素...
该研究利用小鼠、大鼠以及猕猴等多种饮食性肥胖动物模型,研究并证实了由该团队自主开发的可口服小肽D3具有显著的减重作用。该小肽通过靶向“菌肠脑轴”(microbiota-gut-brain axis),刺激肠道上皮细胞产生更多厌食激素(尿鸟苷素,UGN),并促进下丘脑中具有抑食效应的POMC神经元活动增强,降低动物摄食量;此外,该小肽...
nature publishing group Review Gut microbiota, the immune system, and diet influence the neonatal gut–brain axis Michael P. Sherman1, Habib Zaghouani1,2,3 and Victoria Niklas4 The conceptual framework for a gut–brain axis has existed for decades. The Human Microbiome Project is ...
The composition and function of the gut microbiota is robustly influenced by dietary factors to alter gut–brain signalling. To reflect this interconnection between diet, gut microbiota and brain functioning, we propose that a diet–microbiota–gut–brain axis exists that underpins health and well-...
该小肽通过靶向“菌肠脑轴”(microbiota-gut-brain axis),刺激肠道上皮细胞产生更多厌食激素(尿鸟苷素,UGN),并促进下丘脑中具有抑食效应的POMC神经元活动增强,降低动物摄食量;此外,该小肽还可以显著改善肠道菌群平衡,提高嗜黏蛋白阿克曼氏菌(Akkermansia muciniphila)丰度。
was reduced in mice fed a high-fat diet (60% of total energy) for two weeks. They also found that the expression of L-cell-specific genes decreased in mice fed a high-fat diet for sixteen weeks. This suggests a disruption in enteroendocrine cell function and gut-brain axis [169]....
Are brain disorders potentially shaped by the gut microbiota [15]? What role does diet play and what is its scope in influencing the microbiota–gut–brain axis [16, 17]? How do dietary supplements exert their apparent effect(s) on stress, mood, and cognition [18, 19]? What physiological...
The present study aimed to evaluate the effect of β-glucan on the microbiota-gut-brain axis and cognitive function in an obese mouse model induced by a high-fat and fibre deficient diet (HFFD). Results: After chronic supplementation for 15 weeks, β-glucan prevented HFFD diet-induced ...
Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome Increased acetate production by an altered gut microbiota in rats fed a high-fat diet activates the parasympathetic nervous system, which in turn promotes increased insulin secretion, increased food intake, obesity and re...