Like humans with the condition, PLG-deficient mice developed periodontitis, including periodontalbone lossand elevated levels of fibrin in the gums. The mice's gums were crowded with immune cells called neutrophils, which are also found at high levels in common forms of periodontitis. Neutrophils ty...
The finding indicates that GSK3尾 enzyme inhibition in humans may be a method of protecting against the chronic, systemic sequelae associated with periodontal diseases, they add in Molecular Medicine . "The traditional approach to dealing with periodontal disease is to prevent plaque from forming at...
Rapamycin is an immune-suppressing drug currently used to prevent organ rejection in transplant recipients. Previous studies in mice have also suggested that it may have life-extending effects, which has led to interest in studying the drug's effects in many age-related diseases. "We hypothesised ...
- 《Frontiers in Immunology》 被引量: 2发表: 2017年 Hormonal alterations in gum disease leading to preterm labor. The article cites that the relationship between oral infection and systemic diseases are related to periodontal disease. Periodontal disease, which is comm... C Siristatidis,C Nisi...
"DNA from these ancient chewing gums have an enormous potential not only for tracing the origin and movement of peoples long time ago, but also for providing insights in their social relations, diseases and food," says Per Persson at the Museum of Cultural History in Oslo. "Much of our his...
One of the most widespread dental diseases worldwide, the gum disease is defined as inflammation of the gums and damage to the bone and tissues supporting the teeth in the jaws. According to medical literature, people are more likely to show first signs of gum disease in their 30s or 40s,...
Hyperplastic Diseases. Gingival hyperplasia is a simple overgrowth of gum tissue, principally the fibroussubmucosa. The hyperplasia can become severe enough to buryincisorteeth(Fig. 7-40). Gingival hyperplasia is most common inbrachycephalicdogbreeds and is present in 30% ofboxer dogsolder than 5 ...
Objective Periodontal disease is common and frequently-occurring diseases of the dental.The infected with the bacteria to mainly anaerobic bacteria,Gram ne... YM Zhang,WS Xue - 《China Practical Medicine》 被引量: 1发表: 2012年 加载更多
An unhealthy population of microbes in the mouth triggers specialized immune cells that inflame and destroy tissues, leading to the type of bone loss associated with a severe form of gum disease, according to a new study in mice and humans. The research,
Using doxycycline, the most potent of the tetracyclines as enzyme inhibitors, Golub created new formulations of the drug that could be administered not as an antibiotic but as a treatment for chronic inflammatory diseases. The result is the pharmaceutical known as subantimicrobial-dose-doxycline, or...