Introduction:Chronic Heart Failure (CHF) is an epidemic associated with high morbidity and mortality. As per 2022 AHA/ACC/HFSA guidelines, the management of Heart Failure with reduced Ejection Fraction (HFrEF) includes Angiotensin Receptor-Neprilysin Inhibitors (ARNIs), Angiotensin-Converting Enzyme ...
Clinical outcomes of 2,516 patients with worsening heart failure from the BIOSTAT-CHF (BIOlogy Study to Tailored Treatment in Chronic Heart Failure) were compared between 3 theoretical treatment scenarios: scenario A, in which all patients are up-titrated to >50% of recommended doses; scenario B...
CHF congestive heart failure CIED cardiovascular implantable electrical device COR class of recommendation CPP cardiac physiologic pacing CRT cardiac resynchronization therapy CRT-D cardiac resynchronization therapy–defibrillator CRT-P cardiac resynchronization therapy–pacemaker CS coronary sinus CSP conduction syst...
Pharmacological therapy for HFpEF RAS inhibitors have not been proven to improve survival in HFpEF1. On the other hand, the PEP-CHF trial, composed of patients ≥70 years with HFpEF, demonstrated modest clinical benefits of ACE inhibitors at 1 year37. In a cohort of 438 Chinese HFpEF patients...
Abstract 14302: Heart Logic Directed Uptitration of Guideline Directed Medical Therapy Improves EF Across All Device Categoriesdoi:10.1161/circ.148.suppl_1.14302CardiomyopathyImplantable cardioverter defibrillator (ICD)Heart FailureBeta-blockerACE inhibitorIntroduction:Historically data for CHF management in ICD...
Abbreviations: AE: Adverse event; BP: Blood pressure; Ccr: Creatinine clearance; CG: Cockcroft-Gault; CHF: Chronic heart failure; CVA: Cardiovascular accident; CVD: Cardiovascular disease; DM: Diabetes; eGFR: Estimated GFR; GFR: Glomerular filtration rate; Hb: Hemoglobin; KRT: Kidney replacement ...