we performed RNA-seq analysis on UB cells purified from E14.5 mouse kidneys. To determine the dependence on HNF-1β, studies were performed in HNF-1β mutant mice and heterozygous control mice. Using appropriate genetic crosses, we generated Hoxb7/Cre;Hnf1bfl/fl;tdT (HNF-1β mutant...
a mediation analysis based on a framework considering multiple pathways was conducted. Since depression can be preceded by stress, this was considered as potentially health impairing process as opposed to a health promoting process with resilience as a protective factor against the development or mainten...
•Doxorubicin is a cytotoxic drug. Therefore, a Bio-IND is required for bioequivalence studies of a doxorubicin liposome injection to ensure the safety of human test subjects.•The two arms of the crossover study are to be conducted on two of the days when the patients are scheduled to ...
The caretaker used a large-screen (6.3″) Galaxy Note 10 smartphone as the remote terminal. Consistent network availability was achieved with a portable Huawei 4G Wi-Fi router. All VIP participants received an oral introduction to the system and the experiment procedure before the test. They ...
”, “How often did you make use of the possibility to get in touch with an e-coach?”). In order to take these figures into account, the number of inquired feedbacks, as well as the amount of messages e-coaches sent to participants was checked for on the internal platform messaging ...
Based on the BS controller, four error vectors (𝒆1e1 to 𝒆4e4) are defined. Those error vectors and derivatives are expressed as follows: 𝒆1=𝒆2=𝒆3=𝒆4=𝒑−𝒑𝑑(𝛾),𝒆˙1=𝑹𝒗−𝒑˙𝑑,𝒆¨1=−𝑇𝑚𝑹𝒖3+𝑔𝒖3−𝒑¨𝑑𝜎(𝒆1)+...
maps and GIS technology. The influence mechanisms of Nanjing’s urban planning on industrial heritage regeneration and development after 1990 are analyzed. The results show that urban growth boundaries, traffic accessibility, eco-environmental policies, population distribution, industrial renovation investment...
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Jinan Tianhong Community Refinery Industrial Heritage Park was selected as the case study in this paper based on the theory of low maintenance to explore the strategy of superimposed renewal under the guidance of low maintenance and sustainability-oriented superimposed design in the social process; ...
The projection of a point in the scene on the image can be mathematically calculated as shown in Figure 2a. However, given a point of the image it is not possible to obtain directly its original point in the space, as it is not a one-to-one relationship, but one-to-several, thus ...