Professor Guangbin Dong The Dong Group at the University of Chicago has been interested in developing new efficient synthetic methods for site-selective functionalization of complex molecules or allowing for streamlined synthesis of common synthetic building blocks. These include transition metal-catalyzed C...
Zhang, Zining; Zhu, Qi; Pyle, Daniel; Zhou, Xukai* and Dong, Guangbin* “Methyl Ketones as Alkyl Halide Surrogates: A Deacylative Halogenation Approach for Strategic Functional Group Conversions” J. Am. Chem. Soc. 2023, 145, 21096−21103. Liu, Xin; Zhou, Yun; Qi, Xiaotian; Li, ...
This method takes advantage of an exo-imine-type directing group (DG) that can be generated and removed in situ. A range of unprotected aliphatic amines are suitable substrates, undergoing site-selective arylation at the 纬-position. Methyl as well as cyclic and acyclic......
and Dong, Guangbin* "Palladium‐Catalyzed γ‐C(sp3)‐H Arylation of Thiols via a Detachable Protecting/Directing Group" Angew. Chem. Int. Ed. Accepted Manuscript, DOI: 10.1002/anie.201807760 Deng, Lin; Chen, Mengqing; and Dong, Guangbin* "Concise Synthesis of (-)-Cycloclavine and (-)-5...
Zhang, Zining; Zhu, Qi; Pyle, Daniel; Zhou, Xukai* and Dong, Guangbin* “Methyl Ketones as Alkyl Halide Surrogates: A Deacylative Halogenation Approach for Strategic Functional Group Conversions” J. Am. Chem. Soc. 2023, 145, 21096−21103. Liu, Xin; Zhou, Yun; Qi, Xiaotian; Li, ...