( 2001 ) The structural GDP/GTP cycle of human Arf6 . EMBO Rep. 2 , 234 – 238Pasqualato S., Ménétrey J., Franco M., Cherfils J. The structural GDP/GTP cycle of human Arf6. EMBO Reports . 2001; 2 (3):234–238. doi: 10.1093/embo-reports/kve043. [ Cross Ref ]...
The Ras GDP/GTP cycle is regulated by oxidizing agents at the level of Ras regulators and effectors. 来自 Semantic Scholar 喜欢 0 阅读量: 28 作者:K Accorsi,C Giglione,M Vanoni,A Parmeggiani 摘要: Reactive oxygen species (ROS) have been found to play important roles in regulating cellular...
技术领域:本发明属于生物技术领域,具体地说,本发明描述了一种新的多肽——人GTP调控蛋白11,以及编码此多肽的多核苷酸序列。本发明还涉及此多核苷酸和多肽的制备方法和应用。 Ral-GTPase,RalA,RalB,构成了Ras相关GTP结合蛋白家族。和所有的GTPase一样,Ral蛋白与GTP结合后表现出活性,与GDP结合后不表现活性。Ral蛋白的...
Fig. 1. The structural GDP/GTP cycle of human Rab11a. Hydrogen bonds are in dotted lines. A, the Rab11-GDP dimer with the non-crystallographic axis is shown as a broken line. Amino acids and structural elements from the symmetrical molecule are denoted with an asterisk (*). Switch regio...
The two reactions that govern the cycle of these small G proteins, namely GDP to GTP exchange and GTP FRET Assay to Monitor Membrane Translocationof Arf1 on Liposomes In addition to the sedimentation method with sucrose-loaded liposomes, the translocation of Arf1 on artificial liposomes can be ...
The GTP/GDP cycle is believed to control shuttling of Rab proteins between the cytosol and organelle membranes., Rab proteins are removed from membranes by a protein that inhibits GDP dissociation (rabGDI), which leads to formation of a cytosolic complex of Rab with the inhibitor protein. Here...
GTP is also essential tosignal transductioninliving cells, where it is converted toGDPthroughGTPases. Energy transfer GTP is involved in energy transfer within the cell. For instance, one GTP molecule is generated for every turn of theKrebs cycle. This is tantamount to the generation of one ...
'Cyclin A2 plays a key role in cell cycle regulation. It is essential in embryonic cells and in the hematopoietic lineage yet dispensable in fibroblasts. In this paper, we demonstrate that Cyclin A2-depleted cells display a cortical distribution of actin filaments and increased migration. These de...
Isolation and Characterization of a GDP/GTP Exchange Protein Specific for the Rab3 Subfamily Small G Proteins The Rab small G protein family, consisting of nearly 30 members, is implicated in intracellular vesicle trafficking. They cycle between the GDP-bound inact... M Wada,H Nakanishi,A Satoh...
Define GTP. GTP synonyms, GTP pronunciation, GTP translation, English dictionary definition of GTP. n. A nucleotide composed of guanine, ribose, and three linked phosphate groups. It is incorporated into the growing RNA chain during synthesis of RNA and.