null genotypes are seen as having a higher risk of developing leukoplakia. Germline genetic polymorphism in GSTT1 is linked to breast cancer. Clone PAT38D11AT. Physical Appearance Sterile filtered colorless solution. Immunogen Anti-human GSTT1 mAb, is derived from hybridization of mouse F0 myeloma ...
However, a number of studies reported that chemotherapy alone cannot completely eradicate all the cancer cells, especially metastatic cells. Moreover, the mutations of oncogenes such as KRAS, existed in more than 40% of CRC patients, are often associated with poor response of anti-EGFR therapy ...
小鼠抗伤寒Vi多糖IgG抗体检测试剂盒Anti SViP IgGAnti- S.Typhi Vi Polysaccharide IgG37.51200ng/mL1 GST T1 试剂盒科研小鼠兔抗伤寒Vi多糖IgM抗体检测试剂盒Anti SViP IgMAnti- S.Typhi Vi Polysaccharide IgG20640ng/mL1 小鼠羟基类固醇脱氢酶检测试剂盒HSDhydroxysteroid dehydrogenase264U/L0.1 ...
factorsforcancerinahighlyhomogeneouspopulation fromsouthernItaly[J].AntieancerRes,2002,22(6B): 3647—3652. [233 薛开先,许林,陈森清,等.中国人CYP1A1 和GSTM1 基 因多态性及其对个体肺癌易感性的联合效应[J].中华 医学遗传学杂志,2001,18(2):125—127. ...
GSTM1, GSTT1, GSTP1, GSTA1 and colorectal cancer risk: A comprehensive meta-analysis Glutathione S-transferases (GSTs) catalyse reactions between glutathione and lipophilic compounds with electrophilic centres, leading to neutralisation of ... KP Economopoulos,TN Sergentanis - 《European Journal of...
Head and neck squamous cell carcinoma (HNSCC) is a common cancer affecting humans and is responsible for around 600,000 cases and 350,000 tumour-related deaths worldwide each year1. Cisplatin (CDDP) is one of the first-line drugs against HNSCC and is usually administered with radiotherapy (RT...
,R.,... - 《Prostate Cancer & Prostatic Diseases》 被引量: 49发表: 2011年 GSTM1, GSTT1, GSTP1, and GSTA1 Polymorphisms and Urinary Isothiocyanate Metabolites following Broccoli Consumption in Humans1 Isothiocyanates (ITC) are potentially anticarcinogenic phytochemicals formed from the metabolism ...
The most likely explanation is based on the strong anti- oxidant activity of GST enzyme against the damaging effects of oxidative stress. GSTM1 and GSTT1 polymorphisms cause disparities on enzyme activities that can also result in oxidative stress potentia- tion36 through changes on GSH metabolism....
GSTs have been considered to constitute the major defensive anti- oxidant system against oxidative stress by reducing ROS, one of the major factors leading to an infertile status, to less reactive metabo- lites29. Recently, several epidemiological studies have reported that the GSTM1 and GSTT1 ...
Kidd LC, Woodson K, Taylor PR, Albanes D, Virtamo J, Tangrea JA: Polymorphisms in glutathione-S-transferase genes (GST-M1, GST-T1 and GST-P1) and susceptibility to prostate cancer among male smokers of the ATBC cancer prevention study. Eur J Cancer Prev 2003, 12: 317–320...