DRINKING WATER EXPOSURE TO ARSENIC, POLYMORPHISMS IN GSTT1, GSTM1 AND GSTP1 AND METHYLATION CAPACITYcanceroccupational exposurewoodepidemiologyAn abstract is unavailable.doi:10.1097/00001648-200509000-00281McCartyK MHousemanSuQuamruzzamanRahmanMahiuddin...
Download: Download full-size image Figure 3. The catalytic activity of GSTP1 is essential for its anti-ferropototic action (A) Reaction of GSTP1-catalyzed GSH conjugation with CDNB. (B–E) Detection of GST activity (substrate: CDNB) in GSTP1 KD (B and C) or overexpression (D and ...
Full Name glutathione S-transferase pi 1 Synonyms DFN7, FAEES3, Glutathione S transferase P, glutathione S transferase pi 1, GST class pi, GST3, GSTP1, GSTP1 1, PI Calculated Molecular Weight 210 aa, 23 kDa Observed Molecular Weight 23-28 kDa GenBank Accession Number BC010915 Gene Symb...
GST-2YF, GST-2YA and GST-SRC expressed in and purified from E. coil. As shown, significant levels of Tyr phosphorylation of G6PD were only observed with the wild-type G6PD plus ATP (Fig.2K), and the 2YF and 2YA mutants showed a drastic decline of G6PD phosphorylation...
GSTP1; GSTP1; PI; DFN7; GST3; FAEES3; FAEES3; GST3 uniprot entry name : GSTP1_HUMAN clonality : Monoclonal isotype : IgG1 host : Mouse sequence length : 210 specificity : Full length recombinant protein (WB). human GSTP1 recombinant protein (ELISA). Human prostate tissue (IHC) ...
GSTT1, GSTM1, and GSTP1 genes encode enzymes that are among the superfamily of GST enzymes involved in the detoxification of reactive metabolites of carcinogens such as polycyclic aromatic hydrocarbons. Polymorphisms in EPHX1, GSTT1, GSTM1, and GSTP1 genes have been examined as risk factors ...
All the genotypes for all other polymorphisms analysed shared similar frequencies between patients and controls (Pvalue > 0.05 for all these comparisons). The genotype distribution of the six (CAT,GPX,MnSOD,GSTP1,GSTM1, andGSTT1) gene polymorphisms in patients and controls is presented in detail...
Table 1 The distribution of the GST genotypes in Black and Mixed Ancestry in South Africans Full size table Of the 116 subjects who were either homo- or heterozygous for theGSTP1 341C/Tpolymorphism 76% (n = 88) were patients while only 24% (n = 28) were controls. It is important to...
GSTP1 constitutes an important isozyme of the GST enzyme family, which is primarily known for the ability to catalyze the conjugation of the reduced form of glutathione to xenobiotic substrates (e.g., OHP) for the purpose of detoxification [44,45]. Furthermore, genetic variation in GSTP1 ...
2 B), while neither the N-terminal fragment nor buffer conditions produced any change in fluorescence. The calculatedK d for GSTP1–1 association with full-length JNK1 was 188 ± 38 nm and for the C-terminal fragment, 217 ± 72 nm. These data provide quantitative evidence for the direct...