产品别名 GSK-1070806, GSK 1070806, GSK1070806 表达系统 Mammalian Cells 靶标 IFN-gamma-inducing factor, IL1F4, Interleukin-1 gamma, IL-18, IL-1 gamma, Interleukin-18, Interferon gamma-inducing factor, IGIF, IL18, Iboctadekin 宿主 Human 种属反应性 Human 同种型 IgG1-kappa 浓度 3.11 mg/ml...
基本信息 药品名称 GSK1070806 药品类别 创新药; 生物; 抗体 靶点 interleukin 18 (IL-18) 作用机制 anti-IL-18单抗 药品简介 -- 研发机构 GSK 最高研发阶段 全球:II期临床 中国:II期临床 审评审批类型 -- 外置链接 -- 了解药物更多情报 生物序列 ...
Objective: To investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of GSK1070806, a novel IgG1 mAb that neutralizes human interleukin (IL)-18. Methods: In this first-time-in-human (FTIH) study, cohorts of healthy and obese subjects were randomly allocated to receive single...