口服GS-441524治疗猫感染性腹膜炎后完全缓解的猫的长期随访 Long-term follow-up of cats in complete remission after treatment of feline infectious peritonitis with oral GS-441524 導論 猫传染性腹膜炎(Feline infectious peritonitis, FIP)是由猫冠状病毒(Feline infectious peritonitis, FCoV)引起的,它有两种不...
核苷类似物GS-441524治疗自然发生的猫传染性腹膜炎的有效性和安全性 Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis 导…
治疗的较佳剂量为每24h皮下注射4.0mg / kg ,持续至少12周。 References 1.Pedersen, N. C., Perron, M., Bannasch, M., Montgomery, E., Murakami, E., Liepnieks, M., & Liu, H. (2019). Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring...
产地: 美国 保存条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. 纯度规格: 99.9% 产品类别: 抑制剂 货号: T7222 Product Introduction Bioactivity 名称 GS-441524 描述 GS-441524 treatment of cats with naturally occurring feline infectious peritonitis....
GS-441524 treatment of cats with naturally occurring feline infectious peritonitis. Targets&IC50 FIPV:0.78 μM (EC50) In vivo Four of the 31 cats that presented with severe disease died or were euthanized within 2-5 days and a fifth cat after 26 days. The 26 remaining cats completed the pl...
体内活性: Four of the 31 cats that presented with severe disease died or were euthanized within 2-5 days and a fifth cat after 26 days. The 26 remaining cats completed the planned 12 weeks or more of treatment(GS-441524). Eighteen of these 26 cats remain healthy at the time of publicat...
I am inquiring about the availability and pricing of GS-441524 for treating FIP in cats. My cat is currently exhibiting symptoms, and I am looking to begin treatment as soon as possible. Could you provide information on the different packaging sizes, pricing per unit, and shipping options to...
Resistance to GS-441524 can exist at the time of diagnosis, but this is uncommon. Rather, it tends to occur during treatment and is often partial at first and necessitates a higher dosage to accommodate for it. It can become total in some cats. Resistance is the biggest problem in cats ...
for treatment of cats with naturally occurring feline infectious peritonitis》（核苷类似物 GS-441524 ...
The effective concentration-50% (EC50) of GS-441524 is calculated to be 0.78 μM. In Vivo: All 10 treated cats have a rapid response to treatment and lymphocyte levels and rectal temperatures return to pre-infection levels and levels of the two asymptomatic cats. All ten of the once or ...