Scanes CG. Hormones and growth in domestic animals. In: Goodman HM, editor. Handbook of physiology, section 7: the endocrine system. NY: Oxford University Press; 1999. p. 99-127.Scanes CG 1999 Hormones and growth in domestic animals. In: Kosto JL, ed. Handbook of physiology. Oxford: ...
These data subsequently led to the identification of the somatomedin family of hormones (Van Wyk et al., 1974), which are low-molecular-weight peptides (∼7.5 kDa) that circulate in plasma at high concentrations. Because of their structural similarity to proinsulin, they are also termed the ...
Encyclopedia / Pharmaceutical Intermediates / Organic Intermediate / Hormones and synthetic substitutes GROWTH HORMONE, HUMANCAS:9002-72-6 MW:166.19327 MF:C7H6O4GROWTH HORMONE, HUMAN, also known as somatotropin, is a peptide hormone encoded by the GH1 gene in humans. It plays a crucial role in ...
During the first half of the 20th century, clinical observations and anatomical and biochemical studies formed the basis of the understanding of the structure of GH and its various metabolic effects in animals. The following period (1958–1985), during which pituitary-derived human GH was used, ...
Hormones are not found only in humans, but also in all other animals and plants. The variety of different functions hormones have is astounding. Insulin, secreted by the pancreas, regulates the absorption of sugars in the body. Thyroid hormones regulate the rate of cell metabolism and affect ...
The importance of these hormones on the brain has been demonstrated in states of GH/IGF-I deficiency, which results in smaller brains and a variety of organic and functional defects. Hypersecretion of GH/IGF-I, such as in transgenic animals for these hormones, results in larger brains, and ...
Effect of intravenous administration of growth hormone-releasing factor (hpGRF-44) and Tyr-D-Trp-Ala-Trp-D-Phe-NH2 on plasma hormones and metabolites in go... It has recently been demonstrated that human pancreatic GH-releasing factor (hpGRF-44) and Tyr-D-Trp-Ala-Trp-D-Phe-NH2 (subseque...
Growth hormone release is not continuous; it is released in a number of ‘bursts’ or pulses every three to five hours[13]. The pulsatile release of GH into circulation is regulated by the concerted actions of the hypothalamic hormones GH-releasing hormone (GHRH), which stimulates the pituitary...
Treatment with the adrenoceptor (AR) antagonists phentolamine (PHE, α-AR antagonist) and propranolol (PRO, β-AR antagonist) significantly inhibited the CRS-enhanced CRC cell growth in nude mice. In addition, the stress hormones E and NE remarkably enhanced CRC cell proliferation and viability in...
GH-releasing peptides (GHRPs), the first component of the GHS family, were invented rather than isolated in 1977, and are endowed with strong GH-releasing effect both in animals and in humans (1–4). The first GHRPs were derivatives of the pentapeptide Met-enkephalin but devoid of...