The neurohumoral regulation of growth hormone secretion is mediated in part by two hypothalamic peptides, somatostatin and growth hormone-releasing hormone (GHRH). Although somatostatin, a peptide possessing inhibitory activity for growth hormone release, was one of the first of the hypothalamic ...
Growth hormone-releasing hormone (GHRH), a large peptide hormone that exists in several forms that differ from one another only in the number of amino acids, which can vary from 37 to 44. Unlike other neurohormones (substances produced by specialized cel
The meaning of GROWTH HORMONE-RELEASING HORMONE is a neuropeptide released by the hypothalamus that stimulates the release of growth hormone —abbreviation GHRH—called also growth hormone-releasing factor.
GH secretion is stimulated by growth hormone-releasing hormone (GHRH) and is inhibited by somatostatin. In addition, GH secretion is pulsatile, with surges in secretion occurring after the onset of deep sleep that are especially prominent at the time of puberty. In normal subjects, GH secretion ...
Growth hormone-releasing hormone (GHRH) is secreted by the hypothalamus and acts on the pituitary. The latter secretes growth hormone (GH) which, in turn, stimulates the generation in the liver of insulin-like growth factor I (IGF-I), the anabolic effector hormone of GH. All three hormones...
The neurohumoral regulation of growth hormone secretion is mediated in part by two hypothalamic peptides, somatostatin and growth hormone-releasing hormone (GHRH). Although somatostatin, a peptide possessing inhibitory activity for growth hormone release, was one of the first of the hypothalamic releasin...
18 prepubertal growth-hormone (GH)-deficient children were treated with twice-daily subcutaneous injections of a growth-hormone-releasing hormone analogue, GHRH (1-29) NH2. In 12 of the children the height velocity rose on GHRH treatment... RJM Ross,S Tsagarakis,A Grossman,... - 《Lancet》...
Growth hormone (GH) research and its clinical application for the treatment of growth disorders span more than a century. During the first half of the 20th century, clinical observations and anatomical and biochemical studies formed the basis of the understanding of the structure of GH and its va...
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Noun1.growth hormone-releasing factor- a releasing factor that accelerates the secretion of growth hormone by the anterior pituitary body GHRF releasing factor,releasing hormone,RF- a substance produced by the hypothalamus that is capable of accelerating the secretion of a given hormone by the anterio...