The Endocrinologist 17 , 221-226 Online publication date: 1-Jul-2007. /Paul B.Kaplowitz. (2007) Commentary: Is Growth Hormone the Best Treatment for Short Stature in Healthy Peripubertal Boys?. The Endocrinologist 17 , 221-226 /
To determine whether there is evidence for impaired testicular function at final height in short boys treated with growth hormone (GH) during their childhood and adolescence.The analysis was restricted to males who had isolated GH deficiency or idiopathic short stature, and who were included in the...
However, replacement therapy with mecasermin, the recombinant form of insulin-like growth factor-I, may be of substantial benefit in the treatment of this disorder.15 The use of growth hormone in short stature other than that due to indisputable growth hormone deficiency is contro- versial. ...
BiotechnologyMusculoskeletal-disorders, drug-inducedShort-stature, drug-inducedSomatropin, adverse reactionsReactions Weekly -doi:10.2165/00128415-199806940-00007NoneSpringer International PublishingReactions Weekly
In spite of these problems, longitudinal studies are the indispensable base on which thediagnosisandtreatmentof disorders of growth rest, for the clinical approach is a longitudinal one; and each child treated withhuman growth hormone, or with other hormones that affect growth, represents an attempt...
BMI is less than 18.5 kg/m2prior to starting therapy with growth hormone (seeAppendix D); Short-bowel syndrome For a lifetime total of 8 weeks for members with short bowel syndrome (SBS) who depend on intravenous parenteral nutrition for nutritional support when GH will be used in conjunction...
Metabolic balance studies were conducted in seven boys with Duchenne-type muscular dystrophy, and in six normal boys of similar age, during a 12 day control period and during a 12 day period of treatment with human growth hormone (HGH) at the following doses: 0.0168, 0.0532, and 0.168 U/...
The effect of short-term growth hormone or low-dose oxandrolone treatment in boys with constitutional growth delayThe effect of short-term growth hormone or low-dose oxandrolone treatment in boys with constitutional growth delayGHoxandroloneshort statureconstitutional growth delayWe...
Growth hormone decreases lipogenesis and stimulates lipolysis.16, 17 The gain in fat is little in boys after the end of puberty, while girls continue it until 20 years old.2 These gender dysmorphic changes occur after peak height velocity, in the presence of both declining GH secretion and IGF...
In boys, the mainsexhormone istestosterone. This hormone is made in your testicles, two egg-shaped balls which are inside the loose sac under yourpenis. Testosterone helps fuel puberty. Your testicles also producespermcells, the cells that make it possible to get a girl pregnant. ...