Obesity and Growth Hormone Deficiency: A Study of Body Fat DistributionAshraf KamelNermin Salah EldinAbbass MouradHoda Hegazy
10 Hyperinsulinemia and increased plasma free fatty acids associated with obesity also contribute to GH deficiency.8,11 Obesity elevates circulating growth hormone–binding protein (GHBP) concentrations, which may be an adaptive mechanism to increase GH sensitivity in obese subjects.12 View article ...
Endocrine. 2015 Mar 10. [Epub ahead of print]doi:10.1007/s12020-015-0571-4SalvatoriRobertoEndocrineRoberto Salvatori . (2015) Growth hormone deficiency in patients with obesity. Endocrine Online publication date: 10-Mar-2015. /
ObesitySOCS-3Decreased growthhormone (GH) function in obese patients might contribute to associatedmetabolic abnormalities. This study aimed to investigate the effect ofleptin, GH and periods of leptin sensitivity or/and insensitivity on the expressionof the SOCS-3 gene in the ovine pituitary and to...
To discuss the approach to patients diagnosed with growth hormone deficiency (GHD) in childhood during the transition period from puberty to adulthood, focusing on the following: (1) physiology; (2) effects of recombinant human GH (rhGH) interruption/reinstitution after adult height achievement; (...
Growth hormone secretagogue receptor deficiency in mice protects against obesity‐induced hypertension 来自 NCBI 喜欢 0 阅读量: 41 作者:LE Harris,DG Morgan,N Balthasar 摘要: Growth hormone secretagogue receptor (GHS-R) signaling has been associated with growth hormone release, increases in food ...
BMJ 332: 1309–1314 In growth-hormone-deficient adults, hormone replacement can boost cognitive performance Does growth hormone (GH) deficiency and subsequent GH-replacement therapy affect cognitive performance in adults? Falleti et al. performed a meta-analysis of 13 studies to find out. The ...
Current guidelines for the diagnosis of adult growth hormone deficiency (GHD) state that the diagnosis must be proven biochemically by provocative testing that is done within the appropriate clinical context. The need for reliance on provocative testing is based on evidence that the evaluation of spon...
Because homozygous dwarf mice are deficient in growth hormone production, it was concluded that obesity and hyperin-sulinemia can develop under conditions of extreme growth hormone deficiency. 展开 DOI: 10.1016/0026-0495(75)90137-7 被引量: 15 ...
The potential effects of growth hormone (GH) deficiency in adults and the importance of GH secretion in adult life have only been recognized and documented recently. It has been suggested that GH-deficient adults may have premature mortality, abnormalities in body composition and bone density with ...