With the introduction of recombinant human growth hormone (GH), GH-deficient (GHD) children have been treated with larger doses and in a continuous fashion and have been followed to final height. Near-adult height data were reported by Blethen et al. (1) in 121 GHD children who were ...
What is adult growth hormone deficiency (AGHD)?1 Adults can be diagnosed with AGHD in childhood (childhood-onset GHD) and adulthood (adult-onset GHD). Childhood-Onset GHD Most frequent causes: Idiopathic Other causes: Genetic abnormalities and other congenital causes ...
TGHD如为多垂体激素缺乏,可伴有其他垂体激素缺乏的表现,如性腺发育落后等。但对远期并发症的研究集中在成人生长激素缺乏症(adult growth hormone deficiency,AGHD)患者,TGHD远期并发症的研究甚少,需要尽快开展大样本、多中心、长时间的队列研究来进一步明确。 (二)TGHD的评估 儿童期特发性孤立性GHD,尤其是部分性GHD...
Long-term effects:GH therapy normalizes serum IGF-I levels and peripheral thyroid hormone metabolism. Highly significant increments in muscle mass and reductions in fat mass are consistent findings together with increased exercise capacity and muscle strength. GH also restores the decreased extra cellular...
In summary, our study stresses the need for GHD testing in all adult survivors treated with cranial irradiation for a brain tumor in childhood irrespective of radiation modality. Keywords: brain tumor; childhood; survivor; growth hormone; growth hormone deficiency Introduction Brain tumors are the ...
Growth hormone, peptide hormone secreted by the anterior lobe of the pituitary gland. It stimulates the growth of essentially all tissues of the body, including bone, and is vital for normal physical growth in children. Growth hormone is synthesized and
儿童生长激素缺乏症(pediatric growth hormone defi⁃ciency,PGHD)主要表现为身材矮小、生长障碍;PGHD可以是先天性的(遗传、围产期损伤、畸形、身体创伤或垂体柄发育不良),也可以是后天的(肿瘤、手术、感染或放疗);可以是单独的,也可以合并其他垂体激素缺陷[12]。成人生长激素缺乏症(adult growth hormone deficiency,...
To discuss the approach to patients diagnosed with growth hormone deficiency (GHD) in childhood during the transition period from puberty to adulthood, focusing on the following: (1) physiology; (2) effects of recombinant human GH (rhGH) interruption/reinstitution after adult height achievement; (...
百度试题 题目生长激素缺乏症(growthhormonedeficiency,GHD) 相关知识点: 试题来源: 解析 由于垂体前叶合成和分泌生长激素部分或完全缺乏,或由于结构异常、受体缺陷等所致的生长发育障碍性疾病。反馈 收藏
3) growth hormone deficiency 生长激素缺乏 1. Use of cranial MRI in children with growth hormone deficiency 磁共振成像在生长激素缺乏症中的应用 2. Objective To study the relationship between the clinical manifestations and changes of pituitary magnetic resonance imaging(MRI) in short stature ...