Concentrations of five representative growth factors in platelets were measured with enzyme-linked immunosorbent assay (ELISA): platelet-derived growth factor-BB (PDGF-BB), transforming growth factor 尾-1 (TGF-尾1), insulin-like growth factor-1 (IGF-1), vascular endothelial growth factor (VEGF),...
文献:Platelet-rich plasma for androgenetic alopecia: A review of the literature and proposed treatment protocol (雄激素性脱发的富血小板血浆:文献综述及治疗方案)中提到: Platelets in PRP become activated when injected into the scalp and release multiple growth factors, which promote hair growth. These ...
Most of the growth regulatory substances in platelets have been reported to reside in platelet α-granules, but platelet-derived endothelial cell growth factor appears to be present in platelet cytoplasm. These growth factors may act at sites of injury as wound hormones. Moreover, they play ...
Autologous platelet biomaterials represent a key source of cytokines and growth factors extensively used for clinical and surgical applications involving tissue regeneration; wound healing and tissue repair. In this communication we discuss the growth factors released by activated platelet rich plasma (PRP)...
Tumor-derived Platelet-derived Growth Factor-BB Plays a Critical Role in Osteosclerotic Bone Metastasis in an Animal Model of Human Breast Cancer Breast cancer produces a variety of growth factors to promote its behavior at primary and secondary sites in autocrine/paracrine manners. However, the rol...
PaulineBeldon, inSurgery (Oxford), 2010 Growth factors produced by the platelets initiate the healing cascade. Platelet-derived growth factor (PDGF) initiates the chemotaxis ofneutrophilsand macrophages,smooth muscle cellsand fibroblasts, while also stimulatingmitogenesisof smooth muscle cells and fibroblasts...
Platelets contain several growth factors, including vascular endothelial growth factor (VEGF) and insulin-like growth factor. We examined the role of human platelets in liver regeneration with a focus on Kupffer cells (KCs).Severe combined immunodeficiency mice were subjected to 70% hepatectomy and ...
Platelets express receptors for many growth factors/hormones (GFHs). Plasma-circulating GFHs drive signal pathways for transcription in nucleated cells but also drive pathways initiating protein translation from mRNAs. Translation initiation, the rate-limiting step in translation, requires phosphorylation-driv...
Introduction: Platelet derived biomaterials represent a key source of cytokines and growth factors extensively used for tissue regeneration; wound healing and tissue repair. Our study was to quantify platelets and growth factors released by PRP when prepared at different centrifugal force (g) and time...
AIM: Growth factors (GFs) as platelet derived growth factor (PDGF) and transforming growth factor (TGF-beta), found in platelet beta-granules also present in platelet-rich-plasma (PRP), accelerate bone revascularization and regeneration and for this reason they have been employed successfully in ...